The purpose of this study is to develop a mechanistic model to describe a conceptually new "flux-biological response" approach based on biotic ligand model (BLM) and Michaelis-Menten (M-M) kinetics to allow the linkage between valve closure behavior and sodium (Na) transport mechanism in freshwater clam Corbicula fluminea in response to waterborne copper (Cu). We test the proposed model against...

Although gasoline is an important contaminant of aquatic ecosystems, information concerning the potential effects of this petroleum derivative on the DNA of aquatic biota is lacking. The present study aimed to evaluate the genotoxic and mutagenic effects of acute exposures (6, 24, and 96h) to gasoline water-soluble fraction (GWSF), diluted to 5%, on the Asian clam Corbicula fluminea. The comet ...

In order to assess pollutant transfer in Camargue ponds from bordering agrosystems, a biomonitoring assay was conducted in irrigation and drainage channels of rice fields in the Rhone Delta (France). A filter-feeding bivalve, the Asian clam, Corbicula fluminea, was used as bioindicator and caged in upstream and downstream channels of an area of conventional rice fields. After 6 weeks incubation...

Hemagglutinating proteins (HAPs) were purified from Poker-chip Venus (Meretrix lusoria) and Corbicula clam (Corbicula fluminea) using gel-filtration chromatography on a Sephacryl S-300 column. The molecular weights of the HAPs obtained from Poker-chip Venus and Corbicula clam were 358 kDa and 380 kDa, respectively. Purified HAP from Poker-chip Venus yielded two subunits with molecular weights o...

Characterization of uptake and loss dynamics is critical to understanding risks associated with contaminant exposure in aquatic animals. Dynamics are especially important in addressing questions such as why coexisting species in nature accumulate different levels of a contaminant. Here we manipulated copper (Cu) stable isotopic ratios (as an alternative to radioisotopes) to describe for the fir...

Two decades after the first record of invasive mussel Corbicula fluminea (Müller, 1774) in Bulgaria 2001, it has been found many surface lotic and standing waters Bulgarian Danube River Basin.
 The aim current study is to report finding C. environment East Aegean water basin Bulgaria. Six new localities mussel, all situated lower stretches Tundzha (two) Maritsa (four) were registered. dist...

The comet assay was used to study the sensitivity of the widely distributed freshwater bivalve mollusk Corbicula fluminea to the DNA-damaging alkylating-agent methylmethane sulfonate (MMS). This study was undertaken to ascertain if C. fluminea is a good bioindicator of pollutants in aquatic environments and identify which C. fluminea tissue is most effective and practical for genotoxicity studi...

Corbicula fluminea, the primary freshwater bivalve cultivated in Taiwan, was formerly used as a remedy for hepatitis. Recent reports indicate that C. fluminea has many bioactivities, but it remains unknown whether C. fluminea affects inflammation. This study explored the anti-inflammatory activity of C. fluminea. C. fluminea was first treated with chloroform to obtain clam chloroform extracts (...

Arsenic is a potent human carcinogen of skin, lung, and urinary bladder. Freshwater clam Corbicula fluminea is a commercially important native species in Taiwan. C. fluminea is also a suitable biomonitoring test organism. Little is known, however, about the actual effects of arsenic on C. fluminea. The objectives of this study were to provide information on the acute toxicity and bioaccumulatio...

Selenium is essential for most of living organisms. In normoxic to moderately hypoxic freshwaters, Se exists predominantly in the (+VI) and (+IV) oxidation states as selenate and selenite respectively, whereas in the biota it is incorporated as Se (-II) or Se (0). At low concentrations, it acts against oxidative damages, but it may be toxic at higher levels. In filter feeders, such as the fresh...