The molecular responses of macrophages to copper-based nanoparticles have been investigated via a combination of proteomic and biochemical approaches, using the RAW264.7 cell line as a model. Both metallic copper and copper oxide nanoparticles have been tested, with copper ion and zirconium oxide nanoparticles used as controls. Proteomic analysis highlighted changes in proteins implicated in ox...

The interaction of copper oxide nanoparticles and copper ions and proteinase K from Tritirachium album Limber has been investigated employing UV spectroscopy and kinetics measurements. The aim of this study was to evaluate the effect of nanoparticles of CuO for proteinase K. In this paper we compare the effect of copper oxide nanoparticles with the effect of copper ions on proteinase K stabilit...

In the recent decades, metallic nanoparticles have been widely used in various industries due to their wide range of applications1, 2. Nanoparticles have unique electrical, physical, chemical and optical properties3. Nowadays copper is highly regarded due to its specific catalytic, optical, electrical and mechanical characteristics4. Copper nanoparticles have great applications as heat transfer...

Results of research on copper nanoparticles influence on index of readiness to apoptosis and structural changes of liver, spleen, kidney tissues as well as sensomotor cerebral cortex under copper multiple introductions into organism of animals are presented in the article. It is established that copper nanoparticles distribute in organs and tissues of animals and cause specific structural chang...

Chitosan nanoparticles, such as those prepared in this study, may exhibit potential antibacterial activity as their unique character. The purpose of this study was to evaluate the in vitro antibacterial activity of chitosan nanoparticles and copper-loaded nanoparticles against various microorganisms. Chitosan nanoparticles were prepared based on the ionic gelation of chitosan with tripolyphosph...

Copper nanoparticles encapsulated by multi-layer graphene have been produced in large quantity (in grams) by metal-organic chemical vapor deposition at 600 C with copper(II) acetylacetonate powders as precursor. The obtained graphene/copper shell/core nanoparticles were found to be formed by a novel coalescence mechanism that is quite different from the well-known dissolution–precipitation mech...

The interaction of copper oxide nanoparticles and copper ions and proteinase K from Tritirachium album Limber has been investigated employing UV spectroscopy and kinetics measurements. The aim of this study was to evaluate the effect of nanoparticles of CuO for proteinase K. In this paper we compare the effect of copper oxide nanoparticles with the effect of copper ions on proteinase K sta...

The DNA degradation potential and anti-cancer activities of copper nanoparticles of 4-5 nm size are reported. A dose dependent degradation of isolated DNA molecules by copper nanoparticles through generation of singlet oxygen was observed. Singlet oxygen scavengers such as sodium azide and Tris [hydroxyl methyl] amino methane were able to prevent the DNA degradation action of copper nanoparticl...

Objective (s): The green synthesis of copper nanoparticles using metabolites of microorganisms has gained much interest in recent years. In this work, it was studied optimization of copper nanoparticles synthesis using E. coli and its antifungal activity.Materials and Methods: The copper nanoparticles were synthesized by Escherichia coli. Effect of copper nitrate concentration and temperature w...

Metal nanoparticles have gained significant interest in the past decade because of their unique physio-chemical properties which has a potential to be used in a wide range of applications. Recent efforts have gained success in synthesising nanoparticles with excellent shape and size control; however they are largely restricted to chemical methods. There is an increasing focus on eco-friendly ‘g...