نتایج جستجو برای: cope rearrangement

تعداد نتایج: 59498  

Journal: :Organic & biomolecular chemistry 2013
Jik Chin Soon Ho Kwon Kimia Moozeh Soon Mog So Alan J Lough B Moon Kim

Reaction between 1,2-bis(2-hydroxyphenyl)-ethylenediamine (hpen) and methyl pyruvate gives the diaza-Cope rearrangement product with good yield and excellent stereospecificity. The product containing two chiral quaternary carbon centers is characterized by high performance liquid chromatography and X-ray crystallography. DFT computation provides insight into why the diaza-Cope rearrangement tak...

H. Aghaei H. Davoudi M. R Zardoost M. R. Gholami S. A. Radati

A theoretical study of the kinetic and mechanism of 3-aug-Cope rearrangement in gas phase was performed usingDET methods at B3LYP levels of theory with 6-3114iG(d,p) bass set at 298.I5K. Equilibrium moleculargeometries and harmonic vibrational frequencies of the reactant, transition state Did product were calculated. Then,rate constant and activation thermodynamics parameters were calculated an...

Journal: :Organic & biomolecular chemistry 2013
Jonathan D Osler William P Unsworth Richard J K Taylor

The reactivity of a range of substituted divinylcyclopropanes towards the thermal Cope rearrangement has been examined. The effects of gem-dimethyl substitution on the cyclopropane, the alkene geometry, the relative stereochemistry of the cyclopropane and the steric and electronic effects of a range of functional groups were all examined, and the methods developed were used to synthesise a rang...

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