In colloidal probe atomic force microscopy (AFM) surface forces cannot be measured without an accurate determination of the cantilever spring constant. The effective spring constant k depends upon the cantilever geometry and therefore should be measured in situ; additionally, k may be coupled to other measurement parameters. For example, colloidal probe AFM is frequently used to measure the sli...

BACKGROUND This study tests the validity of a newly-proposed spring constant method to analyze arterial elasticity in type 2 diabetic patients. METHODS The experimental group comprised 66 participants (36 men and 30 women) ranging between 46 and 86 years of age, all with diabetes mellitus. In the experimental group, 21 participants suffered from atherosclerosis. All were subjected to the meas...

Hemoglobin Constant Spring is an elongation mutation of the alpha 2-globin locus that results in a thalassemic phenotype. It has a high prevalence in Asian populations. When inherited with other alpha-thalassemia determinants, the Constant Spring gene has the potential to cause severe forms of alpha-thalassemia. Accurate diagnosis of the condition with standard hemoglobin electrophoresis is unr...

Articles you may be interested in Adhesive-free colloidal probes for nanoscale force measurements: Production and characterization Rev. Improved in situ spring constant calibration for colloidal probe atomic force microscopy Rev. Accurate noncontact calibration of colloidal probe sensitivities in atomic force microscopy Rev. A calibration method for lateral forces for use with colloidal probe f...