Toxoplasmosis has been reported with increasing frequency during the last decade, and the various manifestations of the human disease, with particular reference to congenital toxoplasmosis, have recently been summarized by Hutchison (1949), and Wyllie, Fisher, and Cathie (1949). All the cases thus far have been reported from America or Europe, and the case of congenital toxoplasmosis described ...

Aims: To determine whether mothers of children with congenital toxoplasmosis have chorioretinal lesions consistent with toxoplasmosis. Methods: Prospective cohort study. Ophthalmologists in our study have examined 173 children with congenital toxoplasmosis in a hospital outpatient setting. These children were referred to us by their primary care physicians. One hundred and thirty mothers of the...

OBJECTIVE Congenital toxoplasmosis is a public health problem in Brazil. This study aimed to determine risk factors associated with congenital toxoplasmosis in Minas Gerais which is the second largest Brazilian State based on number of inhabitants, and its territorial extension is larger than that of France. METHODS Population-based case-control study to assess the association between congeni...

Toxoplasmosis is a common congenital infection. It does not usually produce recognizable signs of infection at birth so most infected newborns are not detected by routine clinical examination and remain untreated. Infected children without clinical symptoms should nonetheless be identified and treated as early as possible. Serological diagnosis of congenital toxoplasmosis is quite difficult. Th...

UNLABELLED Congenital toxoplasmosis may cause sensorineural deficit in up to 20% of the patients and proper treatment in the first year improves prognosis. In Brazil, this infections impact on hearing impairment is unknown. AIM To evaluate hearing of newborns with congenital toxoplasmosis identified by the newborn screening service. METHOD This prospective study analyzed children with conge...

Toxoplasmosis is caused by the parasite Toxoplasma gondii and is most often a benign disease. Two populations are at risk of severe disease, immunocompromised such as HIV-infected patients and fetuses or children with toxoplasmosis transmitted from their mothers via placenta. Congenital toxoplasmosis is rare on average, less than one case per 1,000 pregnancies, since mother-to-child transmissio...

The clinical value of immunoenzymatic (enzyme-linked immunosorbent assay) detection of anti-Toxoplasma immunoglobulin E (IgE) was assessed by studying 2,036 sera from 792 subjects, comprising seronegative controls and subjects with acute, active, reactivated, or congenital toxoplasmosis. Included were nonimmunized adults; pregnant women with recently acquired infection (acute toxoplasmosis); im...

PURPOSE To describe a case of recurrence of congenital ocular toxoplasmosis with frosted branch angiitis. CASE REPORT A 24-year-old woman presented with hyperemia in her right eye. Medical history included epilepsy at age 14 and mild mental retardation. Iridocyclitis and vitreous opacity were observed in the right eye, and furthermore widespread retinal vessel sheathing due to frosted branch ...

Toxoplasmosis is a rare disease caused by intracellular protozoan parasite, Toxoplasma gondii. Though most patients with toxoplasmosis are asymptomatic, congenital toxoplasmosis in the fetus can cause ocular involvement such as chorioretinitis and central nervous system disease including intracerebral calcification, nystagmus, hydrocephalus and microcephaly. Also, these brain lesions can cause ...