The particle size control of drug is one of the most important factors affecting the efficiency of the nano-drug production in confined liquid impinging jets. In the present research, for this investigation the confined liquid impinging jet was used to produce nanoparticles of Carbamazepine. The effects of several parameters such as concentration, solution and anti-solvent flow rate and solvent...

In the present investigation, slip-continuum and molecular (DSMC) flow models have been used to compare the drag coefficient on a confined microsphere over a range of Knudsen numbers between 0.01 and 0.4. The simulations consider a fixed Reynolds number (Re=0.125) and a range of blockage ratios from 2.0 up to 13.0. Two separate problem formulations have been studied; the first considers flow pa...

In this study, confined impinging liquid jets are used to produce nanoparticles of carbamazepine (CBZ). The effect of operating parameters, such as the kind of solvent,CBZ concentration, flow rate of solution and antisolvent on particle size, are experimentally investigated. The Scanning Electron Micrograph (SEM) photomicrographs show that nanodrug with smaller particle is achievable by usi...