Prothrombin complex concentrates (PCCs) are used mainly for emergency reversal of vitamin K antagonist therapy. Historically, the major drawback with PCCs has been the risk of thrombotic complications. The aims of the present review are to examine thrombotic complications reported with PCCs, and to compare the safety of PCCs with human fresh frozen plasma. The risk of thrombotic complications m...

S. Lobsiger, S. Blaser, R. K. Sinha, H.-M. Frey, and S. Leutwyler*, Nature Chem. 2014, 6, 989. University of Bern 2-Aminopurine (2AP) iswidely used as a site-specific fluorescent probe of DNA and RNA base-flipping and -folding. The group of S. Leutwyler showed that 2AP is not intrinsically strongly fluorescent, contrary to widespread belief. Gas-phase, jet-cooled 2AP and 9-methyl-2AP have very ...

1.5 Range of Application, Dosage, Mode of Administration 1.5.1 Indications 1.5.1.1 General Principles 1.5.1.2 Acute Blood Loss 1.5.1.3 Chronic Anemias 1.5.2 Indications for Special RBC Concentrates 1.5.2.1 Irradiated Leukocyte-Depleted RBC Concentrates 1.5.2.2 Washed RBC Concentrates 1.5.2.3 Cryopreserved RBC Concentrates 1.5.2.4 CMV and Parvovirus B19 1.5.3 Selection and Dosage of RBC Concentr...

Isolated soy-protein products are useful for food ingredients because they provide solubility, water binding, fat adsorption, emulsification, viscosity, gelation, foaming, adhesion and cohesion, texturization, and flavor formation. Soy-protein concentrates (SPCs) and soy (SPIs) are the representative soy Conventionally, SPCs and SPIs have been produced by removing non-protein portions such as o...

BACKGROUND Platelet transfusion is accompanied by febrile nonhemolytic transfusion reactions. The generation of cytokines (like IL-1 beta, IL-6, IL-8, and TNF-alpha) in platelet concentrates by white cells is suggested to be responsible for febrile nonhemolytic transfusion reactions. The number of white cells in the platelet concentrates is crucial to cytokine generation. METHODS This study w...