objective: tabernaemontana divaricata (td) from apocynaceae family offers the traditional folklore medicinal benefits such as an anti-epileptic, anti-mania, brain tonic, and anti-oxidant. the aim of the present study was to evaluate the effect of ethanolic extract of td leaves on burying behavior in mice. materials and methods:mice were treated with oral administration (p.o.) of ethanolic extra...

A key to advancing the understanding of obsessive-compulsive disorder (OCD)-like symptoms is the development of spontaneous animal models. Over 55 generations of bidirectional selection for nest-building behavior in house mice, Mus musculus, resulted in a 40-fold difference in the amount of cotton used for a nest in high (BIG) and low (SMALL) selected lines. The nesting behavior of BIG mice app...

Compulsive smartphone use has received increasing attention due to its ubiquitous and disturbing outcomes. However, integrative research that investigates the process and possible antecedents of compulsive behavior in the use of smartphones remains limited. Based on an extensive review of literature on compulsive behavior, we define compulsive smartphone use in general and explain its specific ...

Impulsive-compulsive sexual behavior is a little studied clinical phenomenon which affects approximately 5% to 6% of the population. In the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition-Text Revision, it is classified as an impulse control disorder not otherwise specified or a sexual disorder not otherwise specified. It may be placed in a possible new category in the Dia...

This study examines the relationship between social motivations, pro-social relationship outcomes, and two types of game play—habitual and compulsive—in the context of simulation games on Facebook. Social motivations were significantly associated with compulsive game play, but not habitual game play. Compulsive play was a positive predictor of pro-social outcomes whereas habitual use was not. B...

Methamphetamine (Meth) users report having heightened sexual pleasure, numerous sexual partners, and engaging in unprotected sex due to loss of inhibitory control. This compulsive sexual behavior contributes to increased prevalence of sexually transmitted infections, but the neural basis for this is unknown. We previously established a paradigm for compulsive sexual behavior in male rats in whi...

Eating disorders and some forms of obesity are characterized by addictive-like, compulsive eating behavior which contains numerous similarities with compulsive drug use. Food intake is in part mediated by reward and reinforcement processes that can become dysregulated in these disorders. Additionally, impairments in inhibitory control regulation of reward-related responding can cause or further...