Background: Quercetin has been reported to modulate cell proliferation and apoptosis. The present study aimed at identifying whether treatment of ionizing radiation (IR) combined with quercetin induces apoptosis in HepG2 cells. Materials and Methods: HepG2 cells were plated at an appropriate density according to each experimental scale and irradiated with 1, 5 and 10 Gy gamma-rays from a 60Co s...

this is an account of the whole work of the institut pasteur de i'iran on rabies: insufficient efficacy of standard method of treatment in the cases of severe bites, particularly of head bites done by rabid wolves: epidemiological and statistical evidences. efficacy of the treatment with the new concentrated antirabies sera, combined with the standard treatment: epidemiological evidences. defin...

Bachground: Today, some treatments like neurofeedback and Vitamin D Supplementation are of great importance in treatment of Attention-Deficit/Hyperactivity Disorder (ADHD). Present literature showed efficacy each of them. For determination of efficacy of combined treatment, this study aims to compare the efficacy of each of them with combined neurofeedback and vitamin D supplementation in the t...

Background: Primary nocturnal enuresis is a common disorder that often leads to considerable distress in affected children and their family. In many countries pharmacologic therapy is preferred to non-pharmacologic behavioral and conditional alarm therapy. Imipramine, oxybutynin, and desmopressin have been used for enuresis with various efficacies. The aim of the present study was to compare th...

Introduction: Cutaneous leishmaniasis is a mutual parasitic disease, which is endemic in some countries of the world. The use of common drugs has been restricted because of confirmed side effects and drug resistance. There are still serious challenges in the treatment of CL. Developing new therapeutic methods for leishmaniasis, besides obtaining a prompt treatment response that...

AIMS/INTRODUCTION To compare the efficacy and safety of early combination therapy with glimepiride/metformin to metformin uptitration in reducing glycated hemoglobin (HbA1c) levels in Korean type 2 diabetic patients inadequately controlled on low-dose metformin monotherapy. MATERIALS AND METHODS In a randomized, open label, parallel group, multicenter study, 209 Korean type 2 diabetic patient...

The efficacy of thalidomide at doses as low as 50 mg every other day was first reported at the VII International Multiple Myeloma Workshop in Stockholm, Sweden, in September 1999. This article discusses the duration of responses with low-dose thalidomide and the subsequent efficacy with thalidomide combination approaches. The median effective dose of thalidomide was 200 mg/d. Thalidomide's mech...