background: primary dysmenorrhea refers to the occurrence of painful menstrual cramps of uterus and is considered as a gynecological complaint. the common treatment for this problem is medical therapy such as mefenamic acid [non‑steroidal anti‑inflammatory drugs (nsaids)] and oral contraceptive pills, both of which work by reducing myometrial activity. fennel contains an antispasmodic and aneth...

introduction: many people are used medicinal plants due to natural, low risks and complications, and low costs as compared with the synthetic drugs. incidence of drug resistance against chemical antimicrobial drugs has led the use of medicinal plants for treatment of infections in recent years. the aim of this study was to examine possible antibacterial effects of four herbal plants in vitro.  ...

Many people have turned away from conventional medicines, with the belief that ‘natural’ substances like herbs are safer than synthetic substances. This belief is augmented by many other unwarranted claims such as herbal products do not contain chemicals while conventional medicines do, thus contributing to the latter’s side effects. The increasing use of herbal medicines has resulted in concer...

Herbal based medicines are used for the treatment of many diseases from ancient times while pharmaceutical chemistry is recently developed. Usually Herbal medicines have been delivered orally in both animals and human. Targeted drug-delivery systems currently more common for the treatment of most life threatening diseases such as cancers. In addition to drug eluting devices many nano based devi...

The ZHENG (syndrome of traditional Chinese medicine) oriented effects and the multiple-targets' mechanism are the main challenges encountered by recent researches for Chinese herbal formula. Using methods of bioinformatics and systems biology, we proposed a biological network-based framework for understanding the mechanism of Chinese herbal formula, and reviewed our studies under this framework...

objective: depression is a major health problem, which is not only underrecognized and undertreated, but is also associated with significant morbidity and mortality. it has been suggested that combination therapy rapidly reduces depressive symptoms in patients with moderate to severe depression and is more effective than monotherapy; but this suggestion remains controversial. serotonergic and n...

glimepiride/metformin(2/500mg) is an oral antihyperglycemic agent for the treatment of type 2 diabetes. a generic glimepiride/metformin(2/500mg) fixed-dose combination(fdc) tablet was developed recently. this study was designed to collect data for submission to korean regulatory authorities to allow the marketing of the test formulation. we evaluated the comparative bioavailability and tolerabi...

Herbal medicines have been used to treat psoriasis for many years with anecdotal reports of efficacy which have attracted public attention. We seek to assess the effects of systemic herbal medicine in the treatment of psoriasis. Medical database PubMed/MEDLINE, AMED, CINAHL, and CENTRAL were searched. Randomised controlled trials of systemic herbal medicine used in the treatment of psoriasis in...