The effect of colony size and age on growth and sexual reproduction was examined by taking small-sized fragments from large mature donor colonies of Goniastrea aspera and Favites chinensis. Both species are massive colonial corals in the family Faviidae. Monopolyp and oligopolyp (5 to 8 polyps) fragments were established. The fragments were cultured in running seawater aquaria for 22 mo, and gr...

Serum stimulates both Ca2+ mobilization and colony growth of many small cell lung cancer (SCLC) cell lines, but the factors involved remain unknown. We demonstrate that 1-oleoyl-lysophosphatidic acid (LPA), like serum, induced a dose-dependent increase in intracellular Ca2+ in the H-510, H-345, and H-69 SCLC cell lines with half maximal concentrations of 18 nM, 22 nM, and 20 nM, respectively. T...

We investigated the effects of human rIL-4 on in vitro hematopoiesis. A profound inhibition of macrophage colony formation by IL-4 was observed, whereas colony growth of other lineages was not affected. Inhibition of macrophage colony growth was not restricted to GM-CSF-induced colony growth but was also present in cultures stimulated with M-CSF. This inhibition was not only observed in culture...

at room temperature (70? to 80?F.) it grows in the form of spreading colonies similar to the ' swarming' Proteus colonies. When incubated at 37?C., the growth is limited to the area of the inoculum. At room temperature the growth continues to spread for three days. If a plate that has been incubated at room temperature and shows a spreading form of growth is subsequently incubated at 37?C., the...

Previous studies have shown that retinoic acid (RA), similar to tumor necrosis factor-alpha (TNF-alpha), can act as a bifunctional regulator of the growth of bone marrow progenitors, in that it can stimulate granulocyte-macrophage colony-stimulating factor (GM-CSF)- or interleukin-3 (IL-3)-induced GM colony formation, but potently inhibit G-CSF-induced growth. The present study, using highly en...

Using four highly polymorphic microsatellite markers (12-28 alleles), we gentoyped workers from 63 colonies of Pogonomyrmex occidentalis. Colonies have a single, multiply mated queen, and an average number of 6.3 patrilines per colony. Colony growth was measured over an 8-year period in the study population. Intracolonial relatedness and colony growth are correlated negatively, indicating a sub...