abstract basement membrane of glomerular mesangium (bmg) is a thin membrane which helps to support the capillary loops in a renal glomerulus and type iv collagen is require for complete bm formation during glomerulogenesis. in this investigation specific antibody of type iv collagen has been used in light microscopy to study development of bmg of the embryonic and postnatal mouse glomerular mes...

objective(s) extracellular matrix (ecm) and basement membrane (bm) play important roles in many developmental processes during development and after birth. among the components of the bm, collagen fibers specially type iv are the most important parts. the aim of this study was to determine the time when collagen type iv appears in the bm of lens structure during mouse embryonic development. mat...

a series of indole-based aryl(aroyl)hydrazone analogs of antiplatelet indole-3-carboxaldehyde phenylhydrazone were synthesized by the schiff base formation reaction and their antiplatelet activity was assessed using human platelet rich plasma. the platelet concentrate was obtained using a two-step centrifugation protocol and adp, arachidonic acid and collagen were used as inducers of platelet a...

background: collagen-based three-dimensional (3d) in vitro systems have been introduced to study the physiological states of cells. as a biomolecule, collagen is usually extracted from terrestrial animals whilst aquatic animals like squid contain large amounts of collagen. methods: in order to make effective use of marine organisms, we selected persian gulf squid in 2015 to extract the required...

This study proceeds to extract collagen from the skin of Rutilus  kutum, one of  the main and economical species of the Caspian Sea. Acid-soluble collagen (ASC) from the skin of R. kutum was extracted and characterized by SDS-PAGE, FTIR and UV spectrophotometry. Based on the data from the SDS-PAGE and the composition of amino acid, it was probable that the obtained collagen classified as type I...

The influence of glycosaminoglycans (GAG) on collagen fibrillogenesis in vitro was investigated. GAG and collagen were isolated from the liver of rats treated with carbon tetrachloride at various time intervals (3-16 weeks). It was found that GAG obtained from the fibrotic liver accelerated collagen fibril formation. This effect was more evident in a solution of type I collagen than type II...

introduction: nowadays the necessity of the existence of a certain width of keratinized gingiva is emphasized upon to maintain periodontal health and prevent soft tissue recession around teeth and dental implants. this study was carried out to compare two gingival graft procedures including connective tissue graft and graft with a combination of collagen sponge with platelet-rich plasma and pla...

background: collagen, the most abundant protein in the human body, and as an extracellular matrix protein, has an important role in the fiber formation. this feature of the collagen renders  establishment of the structural skeleton in tissues. regarding specific features associated with the collagen, such as, formation of the porous structure, permeability and hydrophilicity, it can also be use...

Collagen meshes with large or small openings were prepared after selective removal of PLGA mesh from PLGA–collagen composite collagen-coated mesh. The collagen support human skin fibroblast adhesion and promote cell proliferation.