PURPOSE The aim of our study was to evaluate the effect of in vitro anticancer and cytotoxic activity of the methanolic extracts of 14 medicinal plants, 8 of which are endemic species in Anatolia, against the human HeLa cervical cancer cell line and to compare to the normal African green monkey kidney epithelial cell line (Vero) using the MTT colorimetric assay. METHODS Values for cytotoxicit...

Dracocephalum kotschyi Boiss. is a traditional medicine with antispasmodic activities. The objective of this research was to study antispasmodic activities of hydroalcoholic extract of D. kotschyi on rat isolated uterus contractions for comparison with isolated ileum. Hydroalcoholic extract was obtained from aerial part of D. kotschyi using percolation method. A portion of rat ileum or uterus w...

Caryopses of Aegilops kotschyi Boiss. from different positions within the same spikelet differ greatly in their degree of dormancy. Imposition of this dormancy pattern is a correlative phenomenon within the spikelet, inasmuch as the uppermost developing caryopsis is least dormant and its development is associated with the dormancy status imposed on the lower (one or two) caryopses. Differences ...

Turkey is one of the most important centers of diversity for the genus Achillea L. in the world. Keeping in mind the immense medicinal importance of phenols, in this study, three species growing in Turkey, A. coarctata Poir. (AC), A. kotschyi Boiss. subsp. kotschyi (AK) and A. lycaonica Boiss. & Heldr. (AL) were evaluated for their phenolic compositions, total phenolic contents (TPC), antio...

As a part of a project designed to investigate Colchicum species in Jordan, the chemical constituents of Colchicum crocifolium Boiss. (Colchicaceae) were investigated using LC-MS and LC-UV/Vis PDA. A decision tree for working with colchicinods has been developed by incorporating data from LC-UV/PDA and LC-MS. This dereplication strategy draws upon the UV/PDA spectra to classify compounds into o...

Background & Aim: Iran with about 8000 plant species and 1728 endemic species; is one of the most important sources of medicinal plants. Dracocephalum kotschyi Boiss., belonging to the Lamiaceae family, is one of the endemic plants in Iran. It grows in regions of Chaharmahal and Bakhtiari, Esfahan, Gorgan, Mazandaran, Hamedan, Kermanshah, Lorestan, Tehran, Fars and the northern heights of Semna...

From the whole plant of Dracocephalum kotschyi BOISS., two new monoterpene glycosides (9, 10), together with seven known terpenoids and a phytosterol (1-8), were isolated. Their structures were determined to be limonen-10-al (1), geranial (2), neral (3), beta-sitosterol (4), oleanolic acid (5), ursolic acid (6), p-mentha-8-en-1,2-diol (7), colosolic acid (8), limonen-10-ol 10-O-beta-D-glucopyra...