Background: Familial Mediterranean fever (FMF) has episodic or subclinical inflammation that may lead to a decrease in bone mineral density (BMD). The objective of this study was to assess BMD in Egyptian children with FMF on genetic basis.Methods: A cross sectional study included 45 FMF patients and 25 control children of both sexes in the age range between 3-16 years old. The patients were re...

Recurrent pericarditis is a rare complication following renal transplantation. Colchicine, an inhibitor of microtubule polymerization, has been recommended for the treatment of recurrent acute pericarditis in non-transplant patients and is commonly used for the treatment of gout in transplant patients. However, the use of colchicine for the treatment of recurrent pericarditis in renal transplan...

Familial Mediterranean Fever (FMF) is characterized by recurrent acute attacks of fever and serositis, and colchicine is the primary treatment. The pathogenesis of the disease has not been fully understood. Resistance to colchicine remains to be a problem in up to 30% of the patients and yet there seems to be no alternative treatment. In this study our objective was to investigate whether a sel...

Colchicine has been used to induce chromosome doubling in plant species. Diploid cotton species have inherited desirable genes that are resistant to biotic and abiotic stresses and also possesses useful fiber quality traits, such as higher fiber length and strength. To transfer these desirable traits to the most extensively cultivated tetraploid cotton species through hybridization, it is a pre...

Colchicine treatment enhanced Con A-mediated agglutination of erythrocytes to LM cells (LM is a "spontaneously" transformed mouse line) incubated for brief periods with Con A at 22“ C. Longer incubations with Con A at 22' C rendered colchicine treated cells less agglutinable than untreated cells. Even short incubation times with Con A at higher temperature (37' C) rendered colchicine treated LM...

We present a case of postcardiac injury syndrome with pericardial effusion following cardiac resynchronization therapy implantation which was treated by only colchicine. Although treatment using colchicine is not as common as NSAIDs or steroids, colchicine seems to be an effective and safe treatment option for the syndrome.