A 38-year-old woman was referred to a clinic for evaluation of newly recognized bilateral hilar lymphadenopathy. She denied any pulmonary or systemic symptoms, including recent fevers, chills, weight loss, dyspnea, cough, and chest pain. Fifteen years earlier, the patient suffered from acute interstitial keratitis and acute hearing loss. A diagnosis of Cogan syndrome was made based on the clini...

CLINICAL CASE Patient: A 28 year old man, Caucasian. Chief complain 3/2000: Redness and light sensitivity in both eyes. Past ocular history: Two year history of bilateral keratitis treated with topical steroids with initial improvement and subsequently become unresponsive. Past medical history: Idiopathic hearing loss since 1996, unresponsive to systemic cyclophosphamide and high doses of predn...

SUMMARY Cogan syndrome is an uncommon disorder of unknown etiology characterized by vestibuloauditory dysfunction and nonsyphilitic interstitial keratitis. To our knowledge, the case herein is the first report to demonstrate the cerebral angiographic findings of a patient with this syndrome.

Iridocorneal endothelial (ICE) syndrome encompasses a group of rare ocular pathologies with unilateral involvement, frequently affecting young women. The disease complex includes essential iris atrophy, Chandler's syndrome, and Cogan-Reese syndrome. In the following article, we present a case of Iridocorneal endothelial syndrome in which a late diagnosis was made and who underwent surgery for a...

PURPOSE To determine whether the bony and soft-tissue obliterations of the intralabyrinthine fluid spaces reported in pathologic studies of patients with Cogan syndrome can be detected with MR or CT. METHODS The inner ears of six patients with Cogan syndrome were studied. High-resolution CT was performed in five patients; all six patients were studied with MR, including T1-weighted spin-echo ...

A 43-year-old man presented for neurologic evaluation with acute bilateral hearing loss. Two weeks before presentation, he had bilateral eye pain diagnosed as scleritis. He also noted a subacute history of fevers, night sweats, and diarrhea. Neurologic examination revealed bilateral sensorineural hearing loss, confirmed with audiometry. MRI demonstrated enhancement of the cochlea bilaterally (f...