The cochlea plays a crucial role inmammal hearing.The basic function of the cochlea is tomap sounds of different frequencies onto corresponding characteristic positions on the basilar membrane (BM). Sounds enter the fluid-filled cochlea and cause deflection of the BM due to pressure differences between the cochlear fluid chambers. These deflections travel along the cochlea, increasing in amplit...

Intralabyrinthine schwannomas are rare benign tumors, which arise from neural portions within the labyrinth. These subclassified into seven groups according to affected inner ear structures. Intracochlear (ICS) tumors confined cochlea, and these can cause progressive unilateral sensorineural hearing loss, tinnitus, vertigo aural fullness. Here, we report a 49-year-old female patient with left s...

PURPOSE Treatment uncertainties are not included in modeling dose response of hearing loss. We determine uncertainty of accumulated dose to cochleas of head & neck cancer patients due to setup error during treatments of external beam IMRT. METHODS We studied 8 patients: 1 planning CT for each patient and total 40 cone beam CTs. Those patients were treated with 33 fractions. Treatments deliver...

The active and nonlinear mechanical processing of sound that takes place in the mammalian cochlea is fundamental to our sense of hearing. We have investigated the effects of opening the cochlea in order to make experimental observations of this processing. Using an optically transparent window that permits laser interferometric access to the apical turn of the guinea-pig cochlea, we show that t...

Cochlear implantation is a surgical procedure for treating patients with hearing loss in which an electrode array is inserted into the cochlea. The traditional surgical approach requires drilling away a large portion of the bone behind the ear to provide anatomical reference and access to the cochlea. A minimally-invasive technique, called percutaneous cochlear implantation (PCI), has been prop...

Low-power wide-dynamic-range systems are extremely hard to build. The biological cochlea is one of the most awesome examples of such a system: It can sense sounds over 12 orders of magnitude in intensity, with an estimated power dissipation of only a few tens of microwatts. In this paper, we describe an analog electronic cochlea that processes sounds over 6 orders of magnitude in intensity, and...

This paper presents a new method on the use of gammachirp auditory filter based continuous wavelet analysis. The is designed to provide spectrum reflecting spectral properties cochlea, which responsible for frequency analysis in human system. impulse response theoretical that has been developed by Irino and Patterson can be used as kernel transform approximates cochlea. study implements describ...

The ear is an important sensory organ of the human body. Cochlea has a pivotal role in hearing system human. Nearly 300 million people around world suffer from sensorineural deafness caused by cochlear lesions. Because mechanism sensing very complex, it not been understood completely so far, which become one problems medicine today. basilar membrane canal supporting structure all microstructure...

Laser speckle contrast imaging (LSCI) enables continuous high-resolution assessment of microcirculation in real-time. We applied an endoscope to LSCI to measure cochlear blood-flow in an ischemia-reperfusion mouse model. We also explored whether using xenon light in combination with LSCI facilitates visualization of anatomical position. Based on a previous preliminary study, the appropriate wav...

Members of the neurotrophin gene family and their high-affinity Trk receptors control innervation of the cochlea during embryonic development. Lack of neurotrophin signalling in the cochlea has been well documented for early postnatal animals, resulting in a loss of cochlear sensory neurones and a region-specific reduction of target innervation along the tonotopic axis. However, how reduced neu...