Interactions of cationic tetrakis (N,N´,N´´,N´´´-tetramethyltetra-3,4-pyridinoporphyrazinatocobalt(II) (Co(tmtppa)) with synthetic polynucleotides, poly(A-T), poly(G-C) and calf thymus DNA have been characterized in 5 mM phosphate buffer, pH 7.2, by optical absorption and fluorescence spectroscopy. The appearance of hypochromicity effect and the red shift in UV-Vis spectrum of porphyrazine was ...

In this work, the physicochemical characterization of liposomes loaded with a newly synthesized carboranyl porphyrazine (H2HECASPz) is described. This molecule represents a potential drug for different anticancer therapies, such as boron neutron capture therapy and for photodynamic therapy or photothermal therapy. Different loading methods and different lipid mixtures were tested. The correspon...

The synthesis of magnesium porphyrazines substituted with sulfur-containing 15-crown5 and 18-crown-6 macrocycles is reported as well as the single crystal structure of the 18-crown-6 substituted porphyrazine; the larger crown ether compound is shown to form dimers with Ag+ ions, unlike the porphyrazine with the smaller crown ether rings. Supramolecular structures from phthalocyanine and porphyr...