Bleeding diathesis is a recognised complication of amyloid disease. Localised and generalised bleeding manifestations are usually associated with intravascular coagulopathy related to isolated or multiple coagulation factor deficiencies. Recently, there have been reports of haemorrhage due to amyloid deposition in blood vessel walls and in the perivascular region leading to increased fragility ...

PATIENT Male, 19 FINAL DIAGNOSIS: Hyperleukocytosis • thrombocytosis SYMPTOMS Hyperleukocytosis • retroperitoneal hemorrhage • thrombocytosis MEDICATION - Clinical Procedure: Bone marrow trephine biopsy Specialty: Hematology • Radiology. OBJECTIVE Diagnostic/therapeutic accidents. BACKGROUND Bone marrow (BM) trephine biopsy is generally a safe procedure, but adverse events such as retro...

BACKGROUND Coagulopathy in traumatic brain injury (TBI) has been associated with poor neurological outcomes and higher in-hospital mortality. In general principle of trauma management, hypothermia should be prevented as it directly worsens coagulopathy. Therefore, we examined the safety of mild therapeutic hypothermia (MTH) in patients with coagulopathy following severe TBI. METHODS We re-eva...

Coronavirus disease 2019 (COVID-19) mainly manifests as a respiratory syndrome, besides causing other complications. Severe COVID-19 may also present with coagulopathy, leading to venous thrombosis and cerebral infarction. Generally, acute stroke is secondary complication in patients displaying syndromes. Here, we case of an 84-year-old female patient who did not manifest any symptoms. The had ...

BACKGROUND To assess the safety of percutaneous dilational tracheostomy (PDT) performed by experienced operators in critically ill patients with liver disease and coagulopathy. METHODS Prospective cohort study in a ten bed specialist liver intensive care unit of a tertiary university teaching hospital. Sixty consecutive patients in need of tracheostomy insertion. Patients were categorized as ...

CONTEXT Pancreatitis can be associated with significant complications. Bowel hematoma is a rare complication and the second part of the duodenum is the most commonly affected site. Hematomas affecting other parts of the bowel are extremely rare. CASE REPORT A 53-year-old female with a history of atrial fibrillation and ischemic heart disease on anticoagulants and aspirin presented with abdomi...

Disseminated intravascular coagulation (DIC) with excessive fibrinolysis (XFL) is a rare and acute life-threatening variant of DIC in patients with prostate cancer. Patients present with coagulopathy, hypofibrinogenemia, and systemic bleeding. We describe a case of DIC XFL caused by prostate cancer (PC) successfully treated with a single injection of degarelix, a gonadotropin-releasing hormone ...

Amniotic fluid embolism (AFE) is an unforeseeable, life-threatening complication of pregnancy with extremely high mortality rate. This a complex disorder classically characterized by the abrupt onset hypoxia, hypotension and consumptive coagulopathy. We experienced patient who underwent caesarean delivery because sudden cardiovascular collapse. Intra op she had DIC was hemodynamically unstable....

Hemorrhage is a rare complication of acute cholecystitis. Patients who develop this complication often are receiving anticoagulation therapy or have a pathologic coagulopathy. We present a case of an elderly patient who developed hemorrhagic cholecystitis while taking aspirin and cilostazol, a phosphodiesterase inhibitor. The patient underwent an emergent abdominal exploration. A large, blood-f...

INTRODUCTION Intracranial hemorrhage usually occurs as a complication of hypertension, coagulopathy, or trauma. In rare instances, remote cerebellar hemorrhage (RCH) may complicate supratentorial or spinal surgery. METHODS Retrospective case series study. RESULTS We describe three cases of RCH complicating spinal and cranial surgical procedures associated with cerebrospinal fluid hypotensio...