hemophagocytic syndrome (hps) is an uncommon manifestation in systemic lupus erythematosus (sle). clinical features of hps include fever, pancytopenia, abnormal liver enzyme, hepatosplenomegaly, lymphadenopathy, and coagulation disorder. hps comprises primary and reactive forms. herein, we describe a case of untreated sle with hps as one of the first manifestations of systemic lupus.

congenital factor x deficiency is a rare autosomal recessive bleeding disorder that presents with variable bleeding tendency and prolonged coagulation tests, prothrombin time, and partial thromboplastin time. thromboembolic events have not been reported in patients with factor x deficiency yet. herein, we report a patient with factor x deficiency who had recurrent venous thromboembolic events.

background: hemophilia b is a bleeding disorder with a recessive x-linked inheritance pattern, in which the infected individuals have low levels of factor ix in their plasma. affected individuals may have bleeding episodes after trauma or spontaneously considering the plasma level of factor ix. in order to prevent these episodes and to control bleeding, they should use coagulation factor concen...

Background: Hemophilia B is a bleeding disorder with a recessive X-linked inheritance pattern, in which the infected individuals have low levels of factor IX in their plasma. Affected individuals may have bleeding episodes after trauma or spontaneously considering the plasma level of factor IX. In order to prevent these episodes and to control bleeding, they should use coagulation factor concen...

Bachmann and coworkers in Chicago have performed a careful study of coagulation parameters after cardiopulmonary bypass surgery .1 In 512 patients, they found a 4% incidence of postoperative bleeding. More than half of these cases were due to surgically correctable causes. About 2% of the population were considered to be bleeding because of an acquired coagulation disorder. One half of these ca...

Congenital factor X deficiency is a rare autosomal recessive bleeding disorder that presents with variable bleeding tendency and prolonged coagulation tests, prothrombin time, and partial thromboplastin time. Thromboembolic events have not been reported in patients with factor X deficiency yet. Herein, we report a patient with factor X deficiency who had recurrent venous thromboembolic events.

(A review of the blood coagulation system of fish). Hemostasis is a function of paramount importance when an animal is responding to an injury or has a blood coagulation disorder. It is important to stop the bleeding after a vascular injury, in order to prevent blood loss, so the body needs an effective coagulation mechanism. In fish, despite the fact that there are many studies about the intri...

Sepsis almost invariably leads to hemostatic abnormalities, ranging from insignificant laboratory changes to severe disseminated intravascular coagulation. There is compelling evidence from clinical and experimental studies that disseminated intravascular coagulation is involved in the pathogenesis of microvascular dysfunction and contributes to organ failure. Data from the PROWESS phase III cl...