Colorless alkylmolybdates(VI) of composition R-M0O3are generated in aqueous solutions by the alkaline hydrolysis of complexes R-Mo(Bpy)(0)aBr (Bpy = 2,2'-bipyridyl, R = CH3 and higher alkyl). At room temperature in alkaline aqueous solution, the new organometallic derivatives of oxomolybdate(VI) are remarkably resistant against Mo-C bond hydrolysis. Decomposition occurs more rapidly on heating,...

A series of novel cyano-bridged mixed-valent copper complexes with different nuclearities, where the cyanide group is obtained from the cleavage of a carbon-carbon (C-C) bond in acetonitrile under mild conditions, have been prepared and structurally characterized via a completely in situ synthetic method. The method is catalyzed by 2,2'-bipyridine and 1,10-phenanthroline-based Cu(II) complexes ...

Cain/cabin1 is an endogenous inhibitor of calcineurin (Cn), a calcium-dependent serine/threonine phosphatase involved in various cellular functions including apoptosis. We show here that during apoptosis cain/cabin1 is cleaved by calpain at the carboxyl terminus to generate a cleavage product with a molecular mass of 32 kDa as a necessary step leading to Cn-mediated cell death. Mouse cain/cabin...

a simple, efficient and clean procedure has been developed for the cleavage of imines c=n bond. deprotection of imines to their parent carbonyl and amine compounds was achieved using p-toluenesulfonic acid in the solid state condition at 25-45 ˚c. the salient features of this methodology are shorter reaction times, cheap processing, high yields of product and easy availability of the catalyst. ...

A Ni(ii) complex with two t-butylisocyanide ligands supported by a N3C(-) type tetradentate ligand was synthesized and characterized. Quantitative generation of the aromatic cyanation product, (tBu)N3C-CN, is observed by reacting this Ni(ii) complex with 1 equiv. of an oxidant. Reactivity studies suggest that this oxidatively-induced cyanation involves a heterolytic cleavage of the N-(t)Bu bond...

Cyclic voltammetry and spectroelectrochemistry (e.p.r.) were used to investigate the mechanisms implied in electrocarboxylation of chloroacetonitrile (Cl-CH2-CN, noted RCl) mediated by [Ni(II)(terpy)2]2+. The oxidative addition on electrogenerated [Ni(I)(terpy)]+ yields an alkyl-nickel R-Ni(III) complex which is reduced into alkyl-nickel(II). E.p.r study shows that homolytic nickel-carbon bond ...

The nickel(0) fragment [(dippe)Ni] has been found to react with a variety of aromatic nitriles. Initial pi-coordination to the C=C and Ctbd1;N bonds of 2-cyanoquinoline is found to lead ultimately to C-CN oxidative addition. 3-Cyanoquinoline reacts similarly, although no eta(2)-CN complex is observed. 2-, 3-, And 4-cyanopyridines react initially to give eta(2)-nitrile complexes that then lead t...

Oxygenation of Ir(2)(II,II)(tfepma)(2)(CN(t)Bu)(2)Cl(3)H (1, tfepma = CH(3)N[P(OCH(2)CF(3))(2)](2)) furnishes Ir(2)(II,II)(tfepma)(2)(CN(t)Bu)(2)Cl(3)(OOH) (2), the first isolable iridium hydroperoxo complex. This complex transfers an oxygen atom to triphenylphosphine, producing triphenylphosphine oxide and Ir(2)(II,II)(tfepma)(2)(CN(t)Bu)(2)Cl(3)(OH) (3) in high yield. Reaction of 2 with acid ...