Abstract Background: Considering the fear of drug addicts from hangover symptoms and the costs of withdrawal treatment and their importance in deciding to withdraw, it is helpful to identify various ways of withdrawal and their effects. This study investigated the withdrawal symptoms of two methods of detoxification with clonidine and rapid detoxification of clonidine with naltrexone....

Objective: The objective of the study was to comparison alprazolam versus clonidine and pregabalin as pre-anesthetic medication in patients undergoing elective lower limb surgeries. Methods: present undertaken compare effects 0.5 mg, 100 μg, 75 mg premedicant drugs for reduction pre-operative anxiety. 90 ASA Grades I II, between 18 60 years, either sex, surgery were divided into three groups 30...

Implication for health policy/practice/research/medical education: Clonidine, a relatively old anti-hypertensive agent, has been used during the last years, as an analgesic agent. Nowadays, this drug has been used not only orally, but also, intravenously and interathechally; which possibly suggest newer mechanisms. There are emerging evidence for this fact. Copyright © 2011, ISRAPM, Published b...

conclusions preemptive clonidine has many marvelous advantages over midazolam, including better sedation inside the operating room and then in the post-operative care unit, lower fentanyl doses are required during surgery, more stable heart rate and blood pressure are observed during the procedure, and patients report lower post-operative pain scores. objectives to compare the effect of preempt...

purpose: today considerable advances have been achieved in application of nano-particles.   fullerene is one of the artificial forms of carbon element. long life cycle of medicines in the   human body is a success factor in delivery of medicine to the specific place. lots of nanoparticles   are being developed in this field and from a medical point of view, achieving such   goals is vital. the ...

aim and background:   shivering is a common post anesthesia complication. intravenous methods and materials:   in a rct, 60 adult patients in asa class 1 & 2 scheduled for   c . at the end of the anesthesia, the patients’ shivering was evaluated in the findings:   there was no difference at decrease of spo2 & h.r. & map between 2 groups. there conclusions:   0.2 mg clonidine tablet, 2 hours bef...

BACKGROUND Induction of therapeutic hypothermia is often complicated by shivering. Nefopam reduces the shivering threshold with minimal side effects. Consequently, nefopam is an attractive component for induction of therapeutic hypothermia. However, nefopam alone is insufficient; it will thus need to be combined with another drug. Clonidine and alfentanil each reduce the shivering threshold. Th...

This is a comparative study of the analgesic effects of the modified traditional method of analgesia, electroacupuncture (EA), a standard analgesic drug, morphine, a potential analgesic drug, clonidine and the combination of EA + morphine and EA + clonidine. In each case, the index of analgesia (IA) was determined by recording the tail flick latency (TFL) in 60 rats divided into 6 groups of 10 ...

BACKGROUND This study compared the success rates of buprenorphine and clonidine in detoxification of heroin-dependents and evaluated the recurrence of drug abuse in patients taking naltrexone in a 6 month follow up. METHODS A double-blind study was carried out in Kerman's psychiatric hospital on heroin-dependents seeking detoxification during the years 2007-2009.These patients were randomized...