The Southampton In Vitro Fertilisation Programme was established in 1986. Since that time the programme has maintained a clinical pregnancy rate of over 25 per oocyte retrieval. Embryos in excess of requirements for fresh transfer have been cryopreserved using controlled rate freezing and Propanediol as a cryoprotectant. Review of the first 75 frozen embryo transfers in natural or clomid induce...

Polycystic Ovarian Syndrome (PCOS), a common disorder of the endocrine system, is diagnosed based on inclusion criteria of an ovulation or oligo-ovulation, clinical signs of hyperandrogenism, and/or presence of polycystic ovaries on ultrasound. Many women with PCOS also have hyperinsulinemia, leading to over production of ovarian androgens. Due to this differential, the use of the insulin-sensi...

BACKGROUND Many studies have been carried out to understand the effect of endometrial thickness on the reproductive outcome while the factors affecting the pattern itself are still unknown. OBJECTIVE To determine the factors such as age and the number of follicles that could affect the endometrial thickness Materials and Methods: This study was conducted as a retrospective study on 680 infert...

Clomiphene Citrate (Clomid, Serophene) was introduced into clinical medicine for the treatment of anovulation in the 1960’s. Its introduction represented a major breakthrough in the medical management for ovulation induction. Prior to Clomiphene, patients with PCOS who were anovulatory had few options besides weight loss and surgical wedge resection of the ovaries. While wedge resection was suc...

Clomiphene Citrate (Clomid, Serophene) was introduced into clinical medicine for the treatment of anovulation in the 1960’s. Its introduction represented a major breakthrough in the medical management for ovulation induction. Prior to Clomiphene, patients with PCOS who were anovulatory had few options besides weight loss and surgical wedge resection of the ovaries. While wedge resection was suc...