The aim of this study was to investigate ANG II induced Ca signaling in freshly isolated afferent arterioles (AA) from two-kidney, one-clip hypertensive (2K1C) rats, which have an elevated plasma and renal angiotensin II (ANG II) level, and different perfusion pressure and vascular tone in the clipped and non-clipped kidney. The Ca responses in vessels from 2K1C and control rats were similar in...