The Hader bar system is a popular bar and clip concept because of its 20-degree clip rotation, simplicity, and versatility. Two procedures may be used to incorporate the Hader nylon clip into a denture base. The direct technique consists of attaching the clip to the denture base as a clinical procedure. With the indirect technique, the clip is attached during laboratory processing. An alternati...

Fibroblast growth factors (FGFs) bind to FGF receptors, transmembrane tyrosine kinases that activate mitogenic, motogenic, and differentiative responses in different tissues. While there has been substantial progress in elucidating the Ras-MAP kinase pathway that mediates the differentiative responses, the signal transduction pathways that lead to directed cell migrations are not well defined. ...

The netrin guidance cue, UNC-6, and the netrin receptors, UNC-5 and UNC-40, guide SDQR cell and axon migrations in C. elegans. In wild-type larvae, SDQR migrations are away from ventral UNC-6-expressing cells, suggesting that UNC-6 repels SDQR. In unc-6 null larvae, SDQR migrations are towards the ventral midline, indicating a response to other guidance cues that directs the migrations ventrall...

This article introduces a new biomedical / open surgical instrument to assist surgeon in applying surgical clips to patient’s body tissue and blood vessel during surgical processes. The new clip delivery system is designed to better the clip’s distal advance through internal clip channel, jaw guiding track, and all other transition areas to keep surgical clip from accidental shooting out during...

CLIPs (cytoplasmic linker proteins) are a class of proteins believed to mediate the initial, static interaction of organelles with microtubules. CLIP-170, the CLIP best characterized to date, is required for in vitro binding of endocytic transport vesicles to microtubules. We report here that CLIP-170 transiently associates with prometaphase chromosome kinetochores and codistributes with dynein...

The effect of removing a renal artery clip 14 to 18 days after its application was studied in two-kidney, one clip hypertensive rats. Blood pressure decreased to a normotensive level within 24 hours after the removal of the clip. The cardiovascular effects of reapplication of the clip and infusion of renin, angiotensin II, and norepinephrine were assessed at that time. Reapplication of the clip...

OBJECTIVE Clip artifacts limit the visualization of intracranial structures in CT scans from patients after aneurysmal clipping with cobalt alloy clips. This study is to analyze the parameters influencing the degree of clip artifacts. METHODS Postoperative CT scans of 60 patients with straight cobalt alloy-clipped aneurysms were analyzed for the maximal diameter of white artifacts and the ang...

BACKGROUND Next-generation sequencing technologies have profoundly impacted biology over recent years. Experimental protocols, such as photoactivatable ribonucleoside-enhanced cross-linking and immunoprecipitation (PAR-CLIP), which identifies protein-RNA interactions on a genome-wide scale, commonly employ deep sequencing. With PAR-CLIP, the incorporation of photoactivatable nucleosides into na...