BACKGROUND AND OBJECTIVES Patients of different ages with gastric cancer (GC) have different clinicopathological features and prognoses. The results for different crowds are limited and controversial. The aim of this study was to investigate the differences in clinicopathological features and prognoses between younger and older GC patients. METHODS From January 2007 to December 2011, a consec...

background: inflammatory breast cancer (ibc), a subgroup of locally advanced breast cancer (labc), is diagnosed based on clinical findings, and seems to be different from other types of labc. the purpose of this study was to compare clinicopathological characteristics and outcomes between inflammatory and non-inflammatory labc patients at breast cancer research center (bcrc), tehran, iran. meth...

BACKGROUND We propose a novel prognostic parameter for esophageal squamous cell carcinoma (ESCC)-hemoglobin/red cell distribution width (HB/RDW) ratio. Its clinical prognostic value and relationship with other clinicopathological characteristics were investigated in ESCC patients. RESULTS The optimal cut-off value was 0.989 for the HB/RDW ratio. The HB/RDW ratio (P= 0.035), tumor depth (P = 0...

Background: Cancer stem cells (CSCs) are a group of tumor cells with self-renewal property and differentiation potential. CSCs play a crucial role in malignant progression of several types of tumors. However, what is still controversial is the clinicopathological relationship between Nanog marker and its prognostic value in the patients with breast cancer. The expression of Nanog in the patient...

PURPOSE AND EXPERIMENTAL DESIGN To test whether plasminogen activator inhibitor-1 (PAI-1) can serve as a candidate marker for the malignancy of esophageal squamous cell carcinoma (SCC), we performed a quantitative reverse transcription-PCR for PAI-1 gene and evaluated the possible relationship between PAI-1 gene expression levels and clinicopathological findings in esophageal SCC. RESULTS Sig...

BACKGROUND The PTCH expression level in esophageal squamous cell carcinoma (SCC) was examined. MATERIALS AND METHODS To test whether PTCH can serve as a candidate marker for esophageal SCC, a quantitative reverse transcription (RT) -PCR for the PTCH gene was performed and the possible relationship between PTCH gene expression levels and clinicopathological findings in esophageal SCC was evalu...

to evaluate the prognostic significance of clinicopathological measurement in the diagnosis of acute myocardial infarction (mi) in sheep, acute mi was induced by ligation of left anterior descending coronary artery (lad). for this purpose, twenty four healthy sheep were divided into the sham-operated or control group (group i, thoracotomy without mi) and the experimental group (group ii, with m...