background: breast cancer is one of the most common malignancies among iranian women; however, its clinicopathological feature is uncertain. we pioneered a genetic counseling program among patients with breast cancer and their families in isfahan. this is the first report of this program. methods: this was a descriptive cross-sectional study on women with breast cancer registered in ala cancer ...

Introduction: Breast cancer is the most common cancer and the leading cause of cancer-related death in women. Clinicopathological variables are important factors in deciding on breast cancer treatment. This study evaluated the association between the recurrence score generated by the Oncotype DX® 21-gene assay and classic clinicopathological variables. Methods: A single-institution retrospect...

Background. Soft tissue sarcoma with a hemorrhagic component that cannot be easily diagnosed by needle biopsy is defined here as soft tissue sarcoma with telangiectatic changes (STST). Methods. We retrospectively reviewed clinicopathological data of STST from 14 out of 784 patients (prevalence: 1.8%) with soft tissue sarcoma. Results. Tumors were found mostly in the lower leg. Histological diag...

background: interleukin-19, a member of the interleukin-10 family of cytokines, contributes to breast cancer pathogenesis. high interleukin-19 expression in breast tumor tissues is associated with poor clinical outcome. this study aimed to assess the changes in serum level of interleukin-19 in breast cancer patients in comparison with normal women and its association with the clinicopathologica...

Presenter: Ammar Javed MD | Johns Hopkins University School of Medicine Background: Premetastatic niche formation in the liver resulting from signaling primary pancreatic ductal adenocarcinoma (PDAC), is suggested to play an important role metastatic spread liver. The impact preexisting disease or parenchymal changes (LD) on rates metastasis PDAC remains unexplored. Methods: A prospectively mai...

background: inflammatory breast cancer (ibc), a subgroup of locally advanced breast cancer (labc), is diagnosed based on clinical findings, and seems to be different from other types of labc. the purpose of this study was to compare clinicopathological characteristics and outcomes between inflammatory and non-inflammatory labc patients at breast cancer research center (bcrc), tehran, iran. meth...

BACKGROUND The relationships between connexin 43 (Cx43) expression and clinicopathological factors, epithelial markers, and CpG island methylation in non-small cell lung cancer (NSCLC) are controversial. The aim of this study was to investigate whether the Cx43 expression related with clinicopathological factors, epithelial markers and methylation status of the Cx43 gene. PATIENTS AND METHODS...