background: women 35-39 years old have a 2–3 fold higher risk of pregnancy-related death than women in their twenties and the risk is even more dramatic for women 40 years and older. objective: the aim of this study was to investigate the association of maternal age with risk of adverse pregnancy and mother outcomes in our setting tehran iran. materials and methods: in this retrospective observ...

background: the adult cardiac surgery databank (acsd) of tehran heart center was established in 2002 with a view to providing clinical prediction rules for outcomes of cardiac procedures, developing risk score systems, and devising clinical guidelines. this is a general analysis of the collected data. methods: all the patients referred to tehran heart center for any kind of heart surgery betwee...

Background: The best method for repairing intertrochanteric fractures is still controversial. The fixation methods includeextramedullary (EM) and intramedullary (IM). Studies that compare IM and EM fixations for unstable hip fractures arerare. In this study, our goal was to compare the efficacy of EM and IM fixation in treatment of unstable intertrochantericfractures.Met...

Outcomes analysis is emerging as a crucial tool in understanding and improving health care. To this end, outcomes research is focused on methodologies for assessing the impact and quality of clinical services and the penetration of new findings. Clinical trials are an important mechanism for generating data to support outcomes research activities. In clinical trials in surgical oncology, there ...

Today there is a constant flow of data into, out of, and between ever-larger and ever-more complex databases about people. Together, these digital traces collectively capture our social genome , the footprints of our society. The burgeoning field of population informatics is the systematic study of populations via secondary analysis of such massive data collections (termed "big data") about peo...

Decision makers in health care are increasingly interested in using high-quality scientific evidence to support clinical and health policy choices; however, the quality of available scientific evidence is often found to be inadequate. Reliable evidence is essential to improve health care quality and to support efficient use of limited resources. The widespread gaps in evidence-based knowledge s...

Clinical practice guidelines (CPG) are useful tools for clinical decision making, processes standardization and quality of care improvements. The current General Social Security and Health System (GSSHS) in Colombia is promoting the initiative of developing and implementing CPG based on evidence in order to improve efficiency and quality of care. The reduction of inequalities in health should b...