INTRODUCTION Colorectal cancer (CRC) ranks among the 10 most common cancers in the world,1 including Indonesia.2 It is the most environmentally-related cancer and in this country sporadic CRC affects 35.2% of people below 40 years old,2 as compared to only 3% in developed countries,3 making it an increasingly important health issue as the disease deprives the country of resources and productivi...

Even though diphtheria vaccination has been routinely done all around the world, some of developing country still reported outbreak. Indonesia declared outbreak in 2017. Diphtheria is characterized by sore throat, fever and formation pseudo-membrane located tonsils, pharynx or nasal cavity. very common children. This study was conducted to determine clinical picture children at Sulianto Saroso ...

Background: Cutaneous vasculitis is defined as the inflammation of blood vessels of the dermis. However cutaneous vasculitis is not a specific disease but a manifestation that can be seen in a variety of settings. We sought to review the clinical manifestations, laboratorial findings, pathological changes and etiologic association of cutaneous vasculitis in patients admitted to Dermatology Depa...

Mitochondrial disorders (MD) represent a clinically, biochemically and genetically heterogeneous group of diseases associated with dysfunction of the oxidative phosphorylation system and pyruvate dehydrogenase complex. Our aim was to illustrate the most common clinical presentation of MD on the example of selected diseases and syndromes. The minimal prevalence of MD is estimated as 1 to 5,000. ...

Clinical manifestations of leishmaniasis are diverse and related to the infecting species, its relationship with the environment and the host immune response. A case of late Andean cutaneous leishmaniasis with extensive manifestation is presented. The case was confirmed through microbiological and immunological studies; identification was performed by cytochrome b gene sequencing and the specie...