The dentigerous cyst is one of the most common developmental odontogenic cysts in the jaw. Occurrence of the bilateral dentigerous cyst is uncommon, and frequently associated with syndromes like basal cell nevus syndrome or cleidocranial dysplasia. There are few reports on the presence of bilateral dentigerous cyst in nonsyndromic patients, and most of these are associated with first and third ...

Several topical and systemic factors have been reported to influence the eruption of teeth. Some of the local lesions include eruption cysts, eruption sequestra, fibrous developmental malformations and dentigerous cysts. The systemic factors include Down’s syndrome, cleidocranial dysostosis, hypothyroidism, hypopituitarism and achondroplastic dwarfism. All these lesions and factors generally in...

Cleidocranial dysplasia (CCD), also known as Scheuthauer Marie-Sainton Syndrome, is a rare autosomal dominant inherited disorder, characterized by general retardation in bone ossification, hypoplastic clavicles and various craniofacial and dental abnormalities. Early diagnosis of CCD can be difficult, because the majority of craniofacial abnormalities become obvious only during adolescence. We ...

Dental anomalies are common congenital malformations that can occur either as isolated findings or as part of a syndrome. This review focuses on genetic causes of abnormal tooth development and the implications of these abnormalities for clinical care. As an introduction, we describe general insights into the genetics of tooth development obtained from mouse and zebrafish models. This is follow...

Supernumerary teeth (ST) are odontostomatologic anomaly characterized by as the existence excessive number of teeth in relation to the normal dental formula. This condition is commonly seen with several congenital genetic disorders such as Gardner's syndrome, cleidocranial dysostosis and cleft lip and palate. Less common syndromes that are associated with ST are; Fabry Disease, Ellis-van Crevel...

hyperdontia or supernumerary teeth in both arches without any syndromic manifestation are extremely rare. supernumerary teeth are commonly associated with gardner’s syndrome, cleft lip and palate, cleidocranial dysplasia and trichorhinophalangeal syndrome. five cases of non-syndromic multiple premolars of maxillary and mandibular arches in indian patients are presented here. this case series re...

BACKGROUND Cleidocranial dysplasia is a developmental anomaly of the skeleton and the teeth. This condition may be inherited, be transmitted as dominant characteristics in either sex, or even may appear spontaneously. It presents with skeletal defects of several bones, like partial or complete absence of clavicles, late closure of the fontanels, presence of open skull sutures and multiple wormi...

BACKGROUND Cleidocranial dysplasia is a rare hereditary skeletal disorder due to heterozygous loss of function mutations in the RUNX2 gene that encodes runt-related transcription factor 2 (RUNX2). Here we report a 52 year-old woman with cleidocranial dysplasia due to a novel RUNX2 mutation. CASE DESCRIPTION A 52 year-old Han Chinese woman presented with short stature and skeletal dysplasia th...

Yunis Varon Syndrome was first discovered by Emilio and Humberto in the year 1980. It affects both genders equal number. Most of infants are with Cleidocranial dysplasia, ectodermal anomalities, distal aphalangia. By characteristic features which including deformity pelvis, dislocation hips , bone fracture, urinary tract abnormalities, central nervous system abnormalities this they have reporte...

The Yunis-Varón syndrome represents a rare autosomal recessive syndrome of easy recognition characterized by defective growth of the cranial bone along with complete or partial absence of the clavicles (cleidocranial dysplasia), absence of thumbs and halluces, distal aphalangia, ectodermal anomalies, growth retardation and poor outcome. The molecular genetic basis is unknown. Here, we report an...