objectivemycophenolate mofetil (mmf) is commonly administered concomitantly with ganciclovir for managingtransplant recipients who infected with cmv. this study was conducted to evaluate the probable effects ofganciclovir on mycophenolic acid (mpa) pharmacokinetic.materials and methodsten kidney transplant recipients who full field inclusion and exclusion criterias enrolled in this study. thefi...

objective: measurement of glomerular filtration rate (gfr) is the best determinant in assessment of kidney function for diagnostic and therapeutic purposes. as extremely accurate methods of gfr measurement (i.e. inulin clearance) are expensive and time-consuming and due to limitations of the 24 hour urine collection method, some formula have been developed for the gfr measurement. here we have ...

the effective factors of forward speed, cylinder rotation, and clearance between a combine’s cylinder and concave on wheat kernel breakage and seed germination were studied in karaj area using a 955 model john dear combine. this study was conducted on three levels of adjustment for each of the variables, 1.2, 1.8 and 2.5 km/hr for forward speed, 800, 900, 1000 rpm for cylinder rotation as well ...

Cystic fibrosis (CF) is an inherited disease that primarily affects the lungs and the digestive system, however, it also affects a number of other organs and systems. More than 90% of mortality of  CF patients is due to lung complications.  Healthy lungs are important for a long life for people with CF, We will discuss two important topics for maintaining respiratory health. Chronic use of drug...

cystic fibrosis (cf) is an inherited disease that primarily affects the lungs and the digestive system, however, it also affects a number of other organs and systems. more than 90% of mortality of  cf patients is due to lung complications.  healthy lungs are important for a long life for people with cf, we will discuss two important topics for maintaining respiratory health. chronic use of drug...

the effect of temperature on the main feeding parameters of mnemiopsis leidyi from the southern caspian sea was studied in 2002. the clearance rates and daily rations were estimated from laboratory experiments in a wide range of temperatures from 12 to 27 ?c for m. leidyi of 12?17 mm in length. clearance rate values changed from 52.5 to 107.3 ml ind-1 h-1. the coefficient q10 in temperature 12 ...

Objective: Measurement of glomerular filtration rate (GFR) is the best determinant in assessment of kidney function for diagnostic and therapeutic purposes. As extremely accurate methods of GFR measurement (i.e. Inulin clearance) are expensive and Time-consuming and due to limitations of the 24 hour urine collection method, some formula have been developed for the GFR measurement. Here we have ...

background: simvastatin is a widely used medication in cardiac care. here we evaluate the role of atp sensitive potassium (katp) channels in simvastatin induced renal protection after renal ischemia/reperfusion (i/r) injury.    methods: a total of 81 male wistar rats, were treated with simvastatin (10 and 20mg/kg/day gavage, one week). some groups received glibenclamide (katp channel inhibitor ...

three strains of nontypeable haemophilus influenzae namely nthi-i , nthi-ii and nthi-iii were isolated from the sputum of patients with bronchitis and identified by biochemical, serological and electron microscopy. the polypeptide patterns of isolates were compared and found to have similar sodium dodecyl sulphate-polyacrylamide gel electrophoresis (sds-page) polypeptide patterns, although some...

The dose dependence of mezlocillin pharmacokinetics was examined in relation to renal function after intravenous doses of 1 and 5 g in 16 subjects with various degrees of renal impairment. Dose and time-average model-independent physiological parameters were calculated from plasma concentration and urinary excretion data. Lack of superimposition of plasma concentration profiles occurred between...