Hello! My name is Peter Lawrence and I am pleased to introduce the December issue of Journal Vascular Surgery highlight four outstanding papers which are freely available for next 2 months. Our Editor's Choice article “Cost-effectiveness transcarotid artery revascularization versus carotid endarterectomy,” by Christina Cui co-authors.1Cui C. Ramakrishnan G. Murphy J. Malas M.B. Cost-effectivene...

smoking, dyslipidemia, and diabetes, the other major risk factors. The increase in risk begins as the blood pressure rises above 110/75 mm Hg (Fig. 1). In older patients, systolic pressure and perhaps pulse pressure are more powerful determinants of risk than diastolic pressure. While systolic pressure and pulse pressure are important risk factors, in our experience they are extremely difficult...

Pseudo-aneurysm of the femoral artery is the most common arterial complication in drug injecting abusers. Scholars in vascular surgery have published debating statements regarding techniques of successful surgical management during last two decades. We present the results of simple arterial ligation in a series of 32 patients presenting with infected femoral pseudo-aneurysm. Most of the patient...

Peripheral arterial disease (PAD), which affects ~10 million Americans, is characterized by atherosclerosis of the noncoronary arteries. PAD produces a progressive accumulation of ischemic injury to the legs, manifested as a gradual degradation of gastrocnemius histology. In this study, we evaluated the hypothesis that quantitative morphological parameters of gastrocnemius myofibers change in a...

Peripheral arterial disease (PAD) is characterized by atherosclerotic blockages of the arteries supplying the lower extremities, which cause a progressive accumulation of ischemic injury to the skeletal muscles of the lower limbs. This injury includes altered metabolic processes, damaged organelles, and compromised bioenergetics in the affected muscles. The objective of this study was to explor...

Peripheral arterial disease (PAD) is a manifestation of systemic atherosclerosis significantly reducing arterial blood to the lower extremities. Up to 12 million people in the USA suffer from PAD with claudication as the most common clinical manifestation. These claudicants have an inability to ambulate with a normal gait secondary to pain and fatigue of ischemic muscles. As the affected muscle...