An investigation was carried out to study the feasibility of using 5% nickel/alumina catalysts synthesized with different methods and metal precursors for hydrogenation tetralin. The were characterized atomic absorption spectroscopy, thermogravimetric analysis, X-ray powder diffraction, photoelectron spectroscopy (XPS), hydrogen chemisorption, surface area pore volume analyses. tested in a cont...

We report an experimental study of the phase bebaviour of a model hard sphere colloid + non-adsorbing polymer mixture sterically stabilised PMMA (radius = 217 nm) and polystyrene (r~ = 12.8 nm ) in cis-decalin. It was found'that the main effect of adding polymer was to expand the fluid-crystal coexistence region of the colloidal suspension, which

The total synthesis of cytotoxic polyketides myceliothermophins E (1), C (2), and D (3) through a cascade-based cyclization to form the trans-fused decalin system is described. The convergent synthesis delivered all three natural products through late-stage divergence and facilitated unambiguous C21 structural assignments for 2 and 3 through X-ray crystallographic analysis, which revealed an in...

für Naturforschung in cooperation with the Max Planck Society for the Advancement of Science under a Creative Commons Attribution 4.0 International License. Dieses Werk wurde im Jahr 2013 vom Verlag Zeitschrift für Naturforschung in Zusammenarbeit mit der Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. digitalisiert und unter folgender Lizenz veröffentlicht: Creative Commons Namen...

A stereocontrolled approach to the cis-decalin framework of clerodane diterpenes and biologically active quinone sesquiterpenes is reported. Starting from an inexpensive optically pure tetrahydroindanone, Birch reductive alkylation builds two new contiguous chiral centers-one of which is quaternary and all-carbon-substituted. Also featured is a highly regioselective diazoalkane-carbonyl homolog...

Condensation of glyoxal, formaldehyde and anilines lead to the formation of 2,4,6,8- tetraphenyl and substituted phenyl 2,4,6,8-tetraazabicyclo [3.3.0] octanes. The reactions are sensitive to pH and temperature. Ortho derivatives of anilines do not participate in this condensation. X-ray structural determination reveals a cis-dienvelope geometery about the two fused rings.

Coloradocin was isolated from a fermentation broth by adsorption onto Amberlite XAD-2. The activity was eluted in MeOH and purified by gel filtration on Shephadex LH-20, followed by liquid-liquid chromatography on diol-bonded silica gel. The last two steps in the purification of this antibiotic included reverse-phase chromatography on C18-bonded silica gel and countercurrent chromatography on a...