BACKGROUND Chronic iron overload (CIO) is associated with blood disorders such as thalassemias and hemochromatosis. A major prognostic indicator of survival in patients with CIO is iron-mediated cardiomyopathy characterized by contractile dysfunction and electrical disturbances, including slow heart rate (bradycardia) and heart block. METHODS AND RESULTS We used a mouse model of CIO to invest...

Extant research has documented that the relationship between the chief information officer and the management team (TMT) has been troubled. An often cited contributing factor to this has been the gap in understanding between the CIO and the TMT. The objective of this study is to examine the development of shared mental models (SMMs) between the CIO and TMT about the role of information systems ...

While top management support is critical to the success of information technologies (IT), little is known about how differences and similarities between the CEO and the CIO influence such support. Accordingly, this research examines the heterogeneity between CEO and CIO as antecedents of organizational support and its impact on competitive position in regards to IT in stable and unstable enviro...

This survey investigates the state and impact of CIOs in China. Results show that most CIOs were in fact operating at the departmental director level, coming from an IT-related background. The main impact of CIO felt by CEOs was improved support for decision-making and organizational efficiency. Whereas CEOs’ assessment of CIO performance was mostly positive, a major portion of CEOs had an ambi...

Information systems (IS) alignment is an important aspect in using information technology to gain business value. A critical part of this process is the existence of a good relationship between the CEO and CIO. However, this relationship is disrupted due to CIO turnover. Using a punctuated equilibrium model perspective, this study examines the organizational impact of CIO turnover and its effec...

Maria Teresa Godinho, CIO-Dep. de Matemática, Instituto Politécnico de Beja, [email protected] Luis Gouveia, CIO-DEIO, Faculdade de Ciências da Universidade de Lisboa, [email protected] Thomas L. Magnanti, Dep. of Electrical Engineering and Computer Science and Sloan School of Management, MIT, Cambridge, [email protected] Pierre Pesneau, Université de Bordeaux 1, Institut IMB, France, P...

Despite the important roles chief information officers (CIOs) play in developing information technology (IT) strategies and carrying out IT plans, prior research has not examined the impact of having a formal CIO position on IT investments and firm performance. Drawing on the upper echelons theory and using data from over 250 US firms over the 1999-2003 period, we address how a firm’s CIO posit...

Leading a business unit’s IT function is more challenging than leading a corporation’s IT function. At the business unit level, a CIO reports to the business unit’s manager and to the corporation’s CIO (Hodgkinson 1996). In comparison, the corporate CIO must establish a relationship with one boss the CEO (DeLisi, Danielson et al. 1998; Kakabadse and Korac-Kakabadse 2000). A further problem is t...

Despite the important roles chief information officers (CIOs) play in developing information technology (IT) strategies and carrying out IT plans, prior research has not examined the impact of having a formal CIO position on IT investments and firm performance. Drawing on the upper echelons theory and using data from over 250 US firms over the 1999-2003 period, we address how a firm’s CIO posit...

This paper highlights the role of the Chief Investigation Officer (CIO) in the public sector. With an increased application of Information Technology to manage government processes and to deliver services to citizens the CIO position has become a significant consideration for this sector. However, due to the unique demands of the public sector, as distinct from the private sector, the role of t...