The physicochemical responses of Delftia acidovorans biofilms exposed to the commonly used antimicrobial chlorhexidine (CHX) were examined in this study. A CHX-sensitive mutant (MIC, 1.0 μg ml(-1)) was derived from a CHX-tolerant (MIC, 15.0 μg ml(-1)) D. acidovorans parent strain using transposon mutagenesis. D. acidovorans mutant (MT51) and wild-type (WT15) strain biofilms were cultivated in f...

The objective of this study was to compare the effectiveness of various combination activators of bovine oocyte following intracytoplasmic sperm injection (ICSI) in terms of cleavage and embryo development. Bovine ICSI oocytes were treated with a variation of treatments of combined or single activators as follows; 30 V for 15 x 2 μsec of electrical pulse +10 μg/mL cycloheximide (CHX),7% ethanol...

PURPOSE To evaluate the effect of an acid containing 2% chlorhexidine (Ac/CHX) or a 2% CHX aqueous solution (Aq/CHX) on the immediate and 5-year bonding properties of resin/dentin interfaces produced by two adhesives. The presence of CHX in these interfaces was also evaluated under micro-Raman spectroscopy. MATERIALS AND METHODS Forty-two molars were ground to expose a flat dentin surface. In...

AIM To compare five different commercial mouth rinses with chlorhexidine (CHX) with respect to their anti-halitosis effect and anti-microbial activity on salivary bacterial counts, following a standardised research protocol. And secondly, to validate the study model proposed in the evaluation of patients suffering from halitosis. PATIENTS AND METHODS Ten volunteers, with a healthy oral status...

The aim of this study was to evaluate the efficiency chlorhexidine digluconate solution (CHX) as an adjunct nonsurgical therapy (NPT) patients with chronic periodontitis (CP), by analyzing presence and quantity periopathogenic microorganisms in subgingival biofilm. DNA extracted from biofilm obtained 40 CP divided into two groups (NPT+CHX NPT alone control) at baseline 2 months after therapy. s...

• Liposomes with chlorhexidine (CHX) were incorporated into chitosan hydrogel. CHX-liposomes-in-chitosan hydrogel significantly reduced inflammatory response. inhibited biofilm formation. S. aureus and P. aeruginosa biofilms. Successful treatment of skin infections requires eradication biofilms found in up to 90 % all chronic wounds, causing delayed healing increased morbidity. We hypothesized ...

Dental implants are an increasingly popular solution to missing teeth. Implants are prone to colonisation by pathogenic oral bacteria which can lead to inflammation, destruction of bone and ultimately implant failure. The aim of this study was to investigate the use of chlorhexidine (CHX) hexametaphosphate (HMP) nanoparticles (NPs) with a total CHX concentration equivalent to 5 mM as a coating ...

INTRODUCTION The purpose of this in vitro study was to determine the chemical composition of the precipitate formed by mixing sodium hypochlorite (NaOCl) and chlorhexidine (CHX) and the relative molecular weight of the components. METHODS Using commercially available CHX gluconate, a 2% solution was formed and mixed in a 1:1 ratio with commercially available NaOCl producing a brown precipitat...

OBJECTIVE To systematically review and evaluate the available scientific evidence on the effectiveness of chlorhexidine dentifrice or gel (CHX DF/gel) compared to chlorhexidine mouthwash (CHX MW) on plaque, bleeding, gingival inflammation and tooth discoloration scores. MATERIAL AND METHODS PubMed-MEDLINE, Cochrane-CENTRAL and EMBASE databases were searched to identify appropriate studies. ...

Microorganisms may persist in the root canal system after therapy (RCT). The purpose of this study was to explore metronidazole (MTR)- and chlorhexidine (CHX)-loaded hydrogels as potential application intracanal medicaments for disinfection. Ultraviolet cross-linked (gGels) were synthesized by GelMA solution photoinitiator, which loaded with MTR (MTR@gGels) CHX (CHX@gGels). gGels, MTR@gGels CHX...