At initial presentation, chronic recurrent multifocal osteomyelitis may mimic acute hematogenous osteomyelitis; however, cultures of affected bone are sterile. Nuclear scintigraphy identifies additional foci of involvement that present concurrently or sequentially. Unlike acute bacterial osteomyelitis, chronic recurrent multifocal osteomyelitis seems unaffected by antibiotic therapy and typical...

Chronic recurrent multifocal osteomyelitis (CRMO) is an inflammatory bone disease usually affecting children. A 9-year old boy presented with recurrent lower extremities pain and discomfort lasting for two years. In every time, symptoms vanished after several weeks. The patient received antibiotics only in one period of bone pain. In other occasions the patient didn’t received any antibiotics. ...

A 10-year-old boy was referred to us for evaluation of FUO accompanied with bone pain in both calves. Three hours after intravenous injection of 13 mCi of 99mTc-MDP, whole body scan in multiple spot views was performed. The scan showed symmetrical areas of diffusely increased tracer uptake in multiple long bones. Histopathologic evaluation confirmed osteosclrosis and fibrotic changes...

To cite: Wong DR, Wong GR, Moussa B, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2016-218957 DESCRIPTION A previously healthy girl aged 15 years presented with a 3-month history of low back pain, lethargy, morning stiffness and nocturnal back discomfort. She had no significant history of weight loss, infective symptoms or neurological symptoms, includi...

Chronic nonbacterial osteomyelitis, or its most severe form, chronic recurrent multifocal is an autoinflammatory bone disease that causes skeletal inflammation characterized by pain and swelling primarily affects children. It a diagnosis of exclusion clinical presentation may mimic underlying infectious processes malignancy. Clinical suspicion for this timely referral to pediatric rheumatology ...