background: chronic obstructive pulmonary diseases (copd) are planned to rank fifth in burden of disease and third with respect to mortality by 2020. carrying out research regarding different aspects of copd is mentioned as important health priorities by academic institutions and governments. the burden of lung disease (bold) initiative was designed a decade ago to develop robust models that ca...

background : there is little evidence about the role of zafirlukast (a highly selective ltd4 antagonist) in chronic obstructive pulmonary disease (copd). the zafirlukast can reduce the need for short-acting rescue β2 agonists, produce fewer exacerbations of asthma and increased quality of life as possible benefits treatment for asthma. the aim of our study was to evaluate the effects of zafirlu...

conclusions although we found a trend towards decreasing spah and improving 6mwd, no statistically significant shift were detected in our outcomes due to inadequate sample size. patients and methods a registered (irct201108257411n1), triple-blind, randomized controlled trial was performed in rasoule akram hospital, tehran, from 2009 to 2011. forty five patients with secondary pulmonary hyperten...

nonencapsulated, nontypeable hemophilus influenzae (nthi) remains an important cause of acute otitis and respiratory diseases in children and adults. nthi bacteria are one of the major causes of respiratory tract infections, including acute otitis media, cystic fibrosis, and community-acquired pneumonia among children, especially in developing countries. the bacteria can also cause chronic dise...

background: chronic obstructive pulmonary disease (copd) is usually considered one of the leading causes of death worldwide, so finding proper therapeutic strategies for this disease is of high importance. in this meta-analysis, we reviewed the existing literature on the efficacy and safety of conventional long acting beta agonists (labas) in copd patients. methods: we searched medline and goog...

background and objective: the main causes of nocturnal hypoxemia are pulmonary diseases or sleep related breathing disorders. in overlap syndrome, the co-existence of chronic obstructive pulmonary disease (copd) and ob-structive sleep apnea (osa), blood oxygen alteration, and hypercapnia may be more severe. we aimed to study hypox-emia markers in osa patients with or without copd. materials and...

objective : patients with chronic physical diseases sometimes show increased loss of function; such patients need more care. anxiety is a well-known symptom that is prevalent among chronic obstructive pulmonary disease patients that can prolong and increase the risk of hospitalization. the purpose of this study was to evaluate the severity of anxiety in the mentioned patients and to examine the...

c-reactive protein (crp) is an acute-phase protein synthesized predominantly by the hepatocytes in response to tissue damage or inflammation. levels of acute-phase proteins rise rapidly, during infection and after injury. we take up the study to correlate serum crp levels with other important predictive markers of outcome in copd. patient with stable copd (no exacerbation in the last two months...

chronic  obstructive  pulmonary  disease (copd)  and  asthma  are  major  public  health problems, which seems to have close association with psychiatric disorders. the present study was conducted to compare the psychological status between asthmatic and copd patients and clarify the relationship with severity of pulmonary obstruction. this cross-sectional study was planned to compare the psych...

conclusions in short term, using the self-management program can lead to increased exercise tolerance and decreased dyspnea in patients with copd; thus, this program is recommended as an effective way to improve the functional statuses of these patients. results there was no significant difference between the groups in exercise tolerance at base line; but, they were significantly different at t...