conclusions spironolactone combined with aceis or arbs leads to reduction of proteinuria in chronic kidney disease and therefore reduction of progression of the disease. objectives the study was designed to assess the effects of spironolactone as the aldosterone antagonist combined with acei or arb drugs to reduce proteinuria in chronic kidney disease to prevent its progression. patients and me...

conclusion vttq can sensitively detect the elasticity changes in patients with ckd, and it can effectively predict renal insufficiency. this technology provides a valuable tool for the assessment of ckd. patients and methods sixty-five patients with ckd and seventy healthy participants were included in this study. a total of 270 kidneys were examined by vttq. the kidney elasticity was expressed...

abstract background: quality of life is a concept, which in recent years is considered as a measure for health in chronic diseases such as kidney diseases. complications of chronic diseases can affect the quality of life in children and their families over time. therefore, empowerment programs are necessary to improve their quality of life. this study aimed to investigate the impact of the fami...

background and objective: endocrine disorders are common in patients with chronic kidney disease (ckd). the aim of the present study is reviewing available literature to give a deep understanding of complexities of endocrine disorders in chronic kidney disease. methods: a narrative reviewing method based on the available literature was approached. findings: generally, when renal function decrea...

abstract objectives: interruption of rennin-angiotensin-aldosterone system has become a leading therapeutic strategy in the treatment of diabetic nephropathy however, aceis and arbs do not uniformly suppress the rennin-angiotensin-aldosterone system. plasma aldosterone levels are elevated in a group of patients despite therapy and this phenomenon known as aldosterone escape or aldosterone break...

chronic kidney disease (ckd) is a major public health problem that often goes unrecognized until late-stagedisease. patients with chronic kidney disease face with uremic toxins and hyperkalemia. also fluid overloadin ckd patients is associated with rapid decline in kidney function. lactulose is a hyper osmotic agent andas a prebiotic plays an important role in regulating serum urea and potassiu...

the rise in the prevalence of chronic kidney disease (ckd) and an increase in the prevalence of obesity in parallel in the recent years is a great concern. ckd increases the rate of cardiovascular disease (cvd) and development of end-stage renal disease, and leads to premature death. although no direct causality link between obesity and ckd can yet be established, this appears highly probable. ...

background: chronic kidney disease is asymptomatic until its last stages and though it is increasing globally, we are faced with paucity of a population-based model to assess this disease, particularly in developing countries. therefore, the aim of this study was to estimate the prevalence and trends of ckd according to a new estimation method.   methods: using multiplier method, we estimated t...

background: chronic kidney disease is asymptomatic until its last stages and though it is increasing globally, we are faced with paucity of a population-based model to assess this disease, particularly in developing countries. therefore, the aim of this study was to estimate the prevalence and trends of ckd according to a new estimation method.   methods: using multiplier method, we estimated t...

recent studies suggested the role of white blood cells (wbcs) in the pathogenesis and complications of type 2 diabetes. increased wbc counts predict mortality in patients with chronic kidney disease (ckd). in this study alterations in wbc subpopulations in diabetic patients with non-dialysis dependent ckd are investigated. this was a cross-sectional study  on 376 participants, including   272 d...