نتایج جستجو برای: chronic dermal toxicity
تعداد نتایج: 622190 فیلتر نتایج به سال:
Comparative toxicity of seventeen pesticides to the Quelea, house sparrow, and red-winged blackbird.
Comparative Toxicity of Seventeen Pesticides to the Quelea, House Sparrow, and Red-Winged Blackbird. SCHAFER, E. W., JR., BRUNTON, R. B., LOCKYER, N. F. AND DE GRAZIO, J. W. (1973). Toxicol. Appl. Phurmacol. 26, 154-157. The acute po LD5,, values of 17 commercial or experimental pesticides were determined for quelea (Quelea quelea), house sparrows (Passer domesticus), and red-winged blackbirds ...
BACKGROUND Anal carcinoma is a rare cancer. Surgical treatment is applied for small superficial tumors of the anal margin, the more advanced disease is treated with concomitant chemoradiotherapy. The aim of our study was to evaluate treatment outcomes in patients treated at the Masaryk Memorial Cancer Institute in 2006- 2010. PATIENTS AND METHODS We reviewed the clinical data of 29 newly diag...
Explanation ..................................................................................................... 227 Evaluation for acceptable daily intake ............................................................ 228 1. Biochemical aspects .......................................................................... 228 1.1 Absorption, distribution and excretion .................................
BACKGROUND Endosulfan has been used for over 50 years. Although most analogs have been discontinued, endosulfan has less environmental persistence. Nevertheless, pressure groups are lobbying for a worldwide ban. The reasons are: possible rodent male reproductive toxicity, other endocrine effects and cancer; human epidemiology, and exposure studies; residues appearing in remote areas of the worl...
prohibitins are chaperone proteins highly conserved among eukaryotes. many different functions have been attributed to prohibitins depending on their tissue expression and sub-cellular localization. prohibitins play a major role in mitochondrial physiology, regulating the stability and the processing of both respiratory chain complex subunits and opa1, a mitochondrial fusion regulating protein....
objective(s): pioglitazone (actos) is one of the most controversial recent oral antidiabetic drugs. it was originally authorized in the european :union: in 2000, and approved as an oral monotherapy for overweight second type of diabetic patients in 2002. it belongs to the thiazolidinedione group which some of its members have been withdrawn from the market due to the hepatotoxicity or cardiotox...
Explanation.................................................................................................... 203 Evaluation for acceptable daily intake .......................................................... 204 Biochemical aspects ................................................................................ 204 Absorption, distribution and excretion ......................................
Regulatory information requirements for pesticides call for submission of acute systemic toxicity data for up to three different exposure routes (oral, dermal, inhalation) for both active ingredients and formulated products. Similar multi-route testing is required in the European Union and elsewhere for industrial chemicals. To determine the value of acute toxicity testing by more than one rout...
Previous research has shown that undenatured type II collagen is effective in the treatment of arthritis. The present study evaluated the broad-spectrum safety of UC-II by a variety of toxicological assays including acute oral, acute dermal, primary dermal irritation, and primary eye irritation toxicity. In addition, genotoxicity studies such as Ames bacterial reverse mutation assay and mouse l...
Objective(s): Silver nanoparticles have been widely used as new potent antimicrobial agents in cosmetic and hygienic products, as well as in new medical devices. Serious concerns have been expressed on the potential health risks of dermal applications of nanosilver containing consumer products (AgNPs), therefore regulatory health risk assessment has become necessary for the saf...
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