This report describes the trends of chorionic villus sampling (CVS) referred for prenatal genetic diagnosis in the past two and a half decades in a Portuguese Center. Our cohort of 491 CVS was mostly performed by the transcervical method at the 12th gestational week. Data collected within the framework of this study relate to the following: sampling method, referral reason versus abnormality an...

background: placenta previa (pp) is an obstetric complication that can affect maternal and fetal morbidity and mortality. its prevalence is rising due to cesarean sections. there is no quantitative data of placenta in pp. in this study, quantitative parameters of placenta in cases with pp in comparison with normally implanted controls were investigated. methods: in this quasi experimental study...

Samples of chorionic villi were obtained in the first trimester by aspiration using a cannula passed transcervically under the guidance of real time ultrasound. In initial studies in 47 anaesthetised patients immediately before therapeutic abortion a method was developed giving a success rate of 89%. In 10 patients successful sampling was performed as an outpatient procedure without anaesthesia...

BACKGROUND Placenta previa (PP) is an obstetric complication that can affect maternal and fetal morbidity and mortality. Its prevalence is rising due to cesarean sections. There is no quantitative data of placenta in PP. In this study, quantitative parameters of placenta in cases with PP in comparison with normally implanted controls were investigated. METHODS In this quasi experimental study...

Chemical studies on the metabolism of glucose, fructose and glycogen in human chorionic villi are reported with the following conclusions: 1) In chorionic villi the level of glucose was the mean value between that of the maternal blood and the fetal blood. The level of fructose was three times as high as that in the fetal blood. 2) Chorionic villi convert glucose into fructose. The best conditi...

There have been many diagnostic techniques using amniotic fluid or placental villi, for which needed puncture of amniotic fluid (amniocentesis) and placental villi sampling (CVS) in early pregnancy. The techniques accompany some risk factors of fetal demise or miscarriage. Also immature fetal lung was diagnosed in preterm births by the chemical or physical property of amniotic fluid obtained by...

Fetal growth depends in part on placental growth. The authors tested placental measures derived from digital images for reliability and to evaluate their association with birth weight and gestational age. A total of 628 women recruited into the Pregnancy, Infection, and Nutrition Study, a prospective cohort study of preterm birth in central North Carolina between 2002 and 2004, delivered single...