OBJECTIVE To evaluate the use of topical mitomycin in choanal atresia repair to reduce the development of granulation tissue and cicatrix. DESIGN AND SETTING Retrospective case series in 2 tertiary care centers. PATIENTS Twenty patients with either unilateral or bilateral congenital choanal atresia underwent repair using the transnasal endoscopic approach, the transpalatal approach, or both...

Unilateral atresia is an extremely uncommon congenital disorder in monozygotic twins. We present the first case in the literature of premature, monozygotic twins with no other congenital genetic defects other than only one twin with unilateral choanal atresia on the right side, being the other sibling completely normal. Diagnostic examinations performed to both twins consisted of nasal endoscop...

OBJECTIVE To present epidemiologic data on the relatively rare malformation choanal atresia, based on a large collection of material and with special stress on the significance of the so-called CHARGE (coloboma, heart defect, choanal atresia, retarded growth and development, genital anomaly, and ear defect with deafness) association. METHODS Data from three large registries of congenital malf...

Congenital choanal atresia (CCA) is the developmental failure of the nasal cavity to communicate with the nasopharynx. Bilateral choanal atresia is potentially life threatening in newborns. Most of these cases present early in life with cyclical phases of respiratory distress and apnoea, which gets relieved by crying. In fewer cases it goes undiagnosed to present in adult life with rhinorrhoea ...

Reported cases of acquired posterior choanal atresia are very few in the English literature. A case of acquired posterior choanal atresia post radiotherapy is reported which was treated by endonasal endoscopic repair using microdebrider with untoward effect.

Unilateral choanal atresia is more common than bilateral cases. Unilateral cases may present later in life with unilateral nasal congestion and mucoid rhinorrhea. Pure bony atresia represents 30% of cases while mixed bony and membranous atresia is more common (70%) [1]. The ideal procedure for management of choanal atresia should restore the normal nasal passage, be safe, prevent damage to any ...

Introduction  The main histological features of the nasal mucosa in choanal atresia are distorted cilia, marked increase of mucous submucosal glands associated with marked reduction of goblet cell density, and lymphocytic cellular infiltration. Objective  To study the nasal mucosal changes in cases of choanal atresia after successful repair compared with pre-repair mucosal histological features...

INTRODUCTION Adult choanal atresia is a rare congenital malformation of the nasal cavity characterized by the complete obliteration of the posterior choanae, only ninth cases are reported in the literature, we present in our observation the tenth case of adult bilateral choanal atresia. PRESENTATION OF CASE A 18-year-old man presented at our department with complaints of nasal obstruction, na...

OBJECTIVE To evaluate the intraoperative use of mitomycin to improve the surgical outcome and reduce the rate of soft tissue restenosis in children undergoing choanal atresia repair. DESIGN Retrospective chart review of all patients surgically treated for congenital choanal atresia by the senior author (W.F.M). SETTING Tertiary children's hospital. PATIENTS Eight consecutive patients with...

BACKGROUND Bilateral congenital choanal atresia that presents in adulthood is rare. There are only eight reported cases in the literature. METHOD We present a ninth case of adult bilateral choanal atresia diagnosed at the age of 20 years. Can a bilateral choanal atresia present so late in life when such a condition is considered incompatible with life? RESULTS AND CONCLUSION Clinical detail...