Background: b-thalassemia major is a common hereditary blood disease that can affect patients’ oral health and quality of life. The present study aims to determine the relationship between health of deciduous teeth and the Oral Health-Related Quality of Life (OHRQoL) in children diagnosed with β-thalassemia major compared with healthy children. Materials and Methods This cross-sectional study w...

Thalassemias are a group of inherited disorders that are characterized by decreased production of the alpha or beta globin chains. The amount of the produced normal hemoglobin within the red blood cells correlates with the severity of the symptoms. Fetuses with alpha-thalassemia major usually die. Children with beta-thalassemia major are usually dependent on repeated blood transfusions. Splenec...

BACKGROUND Iron Deficiency Anemia (IDA) is an important health problem all around the world especially in developing countries. In the Mediterranean countries another prevelant reason of anemia is Thalassemia. Certain strategies had been established as a government policy to reduce prevalence in North Cyprus, such as pre-marital screening of Thalassemia. The prevalence of thalassemia trait has ...

This study aimed to determine differences in the rates of growth, endocrine- and calcium-related abnormalities in the various thalassemia syndromes in North America treated with current therapies. Medical history, physical examinations and blood and urine collections were obtained from patients with all thalassemia syndromes age 6 years and older in the Thalassemia Clinical Research Network. 36...

OBJECTIVE To describe the challenges, including sociocultural and socioeconomic barriers, faced by an urban immigrant population in the United States affected by thalassemia major. DESIGN Ethnographic, semi-structured, 1-on-1 interviews using an interview guide developed for this study. Digital recordings were transcribed and data analyzed using constant comparative method. SETTING Universi...

abstract background thalassemia is one of the most common human genetic diseases in the world and it provides many problems for patients, families and health care system. this model helped the family with sick children to empower to face disease and its complications. to reach this aim, the knowledge and attitude of patients and their families about the disease should be increased. this study w...

introduction: in 1989, the first successful umbilical cord blood transplantations (ucbts) was reported in a boy with fanconi's anemia, using umbilical cord (ucb) of his hla matched sister. cord blood transplantation is a good substitute for bone marrow or peripheral blood transplantation especially for children and small body size adults. methods: between 1998 and 2007 ,14 children(10 boys and ...

Objective: To find out the incidence, characteristics and laboratory parameters of epistaxis in children with β-thalassemia major visiting a tertiary healthcare facility South Punjab, Pakistan. Study Design: Retrospective study. Setting: Department Hematological Disorder, Thalassemia Bone Marrow Transplantation Centre, Biochemistry, Bahawal Victoria Hospital, Quaid e Azam Medical College, Bahaw...

BACKGROUND: Patients with transfusion-dependent thalassemia require lifelong blood transfusions and iron chelation therapy. Iron overload associated regular transfusion leads to a significant defect in the health-related quality of life (HRQoL) patients thalassemia. Quality has become component care, it is therefore necessary focus on HRQoL 
 OBJECTIVES: To assess children thalassemia, ide...