Ethiopia has a diverse ecology and geography resulting in spatial and temporal variation in malaria transmission. Evidence-based strategies are thus needed to monitor transmission intensity and target interventions. A purposive selection of dried blood spots collected during cross-sectional school-based surveys in Oromia Regional State, Ethiopia, were tested for presence of antibodies against P...

Filter paper cards incorporating dried blood spots for the measurement of theophylline concentrations were returned by 62 out of 100 asthmatic children sent kits with instructions for their collection. Analysis of the blood spots showed that 37 (61%) of the children who returned them had less than therapeutic blood theophylline concentrations, in 21 (34%) they were therapeutic, and in three (5%...

We assessed the pharmacokinetics and safety of solithromycin, a fluoroketolide antibiotic, in a phase 1, open-label, multicenter study of 13 adolescents with suspected or confirmed bacterial infections. On days 3 to 5, the mean (standard deviation) maximum plasma concentration and area under the concentration versus time curve from 0 to 24 h were 0.74 μg/ml (0.61 μg/ml) and 9.28 μg · h/ml (6.30...

570 Indian Journal of Dermatology 2016; 61(5) 7. Walker BA, Beighton PH, Murdoch JL. The Marfanoid hypermobility syndrome. Ann Intern Med 1969;71:349-52. 8. Daneshwar A, Tavakoli D, Nazarian J. Marfanoid hypermobility syndrome associated with coarctation of the aorta. Br Heart J 1979;41:621-3. 9. Terada Y, Wanibuchi Y. Surgically treated case of Marfanoid hypermobility syndrome. Ann Thorac Surg...

An outbreak of small angiomatous lesions with the same clinical and histological features as Campbell de Morgan spots in adults is described. No infective agent was discovered, but their number was found to increase as the ambient temperature rose.

The incidence of trypanosomosis was determined using the haematocrit centrifuge technique (HCT) as well as polymerase chain reaction (PCR) on 120 goat blood spots on filter paper. Both techniques failed to detect a positive reaction, implying that factors such as age, healthy appearance and small sample size notwithstanding, trypanosomosis does not seem to pose a serious threat to goat health i...

OBJECTIVE To determine the feasibility of sending dried blood spots (DBS) to an overseas processing center for the diagnosis of HIV infection in infants in rural Haiti. METHODS The program took place in the Central Department of Haiti. Children under 18 months of age who were born to an HIV-infected mother or who had a positive HIV antibody test had blood collected on filter paper. Once dry, ...

Human African Trypanosomiasis (HAT) is a major public health problem in the Democratic Republic of the Congo (DRC). Active and passive surveillance for HAT is conducted but may underestimate the true prevalence of the disease. We used ELISA to screen 7,769 leftover dried blood spots from a nationally representative population-based survey, the 2007 Demographic and Health Survey. 26 samples were...