PURPOSE To conduct a meta-analysis of published studies to determine the construct and criterion validity of the mini-clinical evaluation exercise (mini-CEX) to measure clinical performance. METHOD The authors included all peer-reviewed studies published from 1995 to 2012 that reported the relationship between participants' performance on the mini-CEX and on other standardized academic and cl...

Ferreira A, Prímola-Gomes T, Menezes Z, Cruz J, Natali A. Chronic Treadmill Running Affects Adipose Tissue Metabolism in Spontaneously Hypertensive Rats. JEPonline 2010;13(5): 9-18. We investigated in adipocytes of hypertensive rats (SHR) the effects of chronic treadmill running on parameters influenced by insulin (anti-lipolytic effect, glucose uptake) and on LPL activity. Male SHR were random...

AIMS The cell-surface display of Cex, which encodes xylanase and exoglucanase from Cellulomonas fimi, was constructed on Escherichia coli using PgsA as the anchor protein. Characterization of the cell-surface display of Cex was performed. METHODS AND RESULTS PgsA was fused to the N-terminus of Cex and six histidines were utilized as spacers between the targeting and anchor proteins. Successfu...

Cephalexin (CEX) was synthesized with 7-amino-3-deacetoxycephalosporanic acid (7-ADCA) and D(–)-phenylglycine methyl ester (PGME) using immobilized penicillin G acylase from Escherichia coli. It was found that substrate concentration and in situ product could remarkably influence the ratio of synthesis to hydrolysis (S/H) and the efficiency of CEX synthesis. The optimal ratio of enzyme to subst...

The mini-clinical evaluation exercise (mini-CEX) is a well-established method of assessing trainees' clinical competence in the workplace. In order to improve the quality of clinical learning, factors that influence the provision of feedback are worthy of further investigation. A retrospective data analysis of documented feedback provided by assessors using the mini-CEX in a busy emergency depa...

OBJECTIVE To evaluate the mini-clinical evaluation exercise (mini-CEX), which assesses the clinical skills of residents. DESIGN Observational study and psychometric assessment of the mini-CEX. SETTING 21 internal medicine training programs. PARTICIPANTS Data from 1228 mini-CEX encounters involving 421 residents and 316 evaluators. INTERVENTION The encounters were assessed for the type o...

BACKGROUND The mini-Clinical Evaluation Exercise (mini-CEX) is a workplace-based assessment which may be useful in anaesthesia training. However, its value depends on how supervisors use it with their trainees. This study analyses experience with the mini-CEX after its introduction into anaesthesia departments in our institution. METHODS We conducted surveys, focus groups, and interviews with...

Just as there was a close connection between hypothesis testing with the one-sample t-test and a confidence interval for the mean of a sample, there is a close connection between hypothesis testing and confidence intervals for the parameters of a linear model. We’ll start by explaining the confidence interval as the fundamental idea, and see how this leads to hypothesis tests. ellipse() from th...

An endo-beta-1,4-glucanase (CenA) and an exo-beta-1,4-glucanase (Cex) were prepared from Escherichia coli expressing recombinant DNA of the cellulolytic bacterium Cellulomonas fimi. Purification was facilitated by the high affinities of these enzymes for cellulose. An extracellular C. fimi protease cleaved both enzymes in vivo in a highly specific manner. The affinity of the parent enzyme for c...