V arious studies (1–16) in recent years have reported that the metabolic syndrome is associated with an increase in cardiovascular disease (CVD). However, there is still an uncertainty about the clinical importance and consequences of the metabolic syndrome (17). There is paucity of data looking at the effect of metabolic syndrome, specifical ly on cerebrovascular (CeVD) (9,12,18,19) and periph...

BACKGROUND Atherosclerosis is an important predictor of mortality in patients with end-stage renal disease. The aim of this study was to determine how various vascular comorbidities such as coronary heart disease (CHD), peripheral vascular disease (PVD) or cerebrovascular disease (CeVD) affect survival of type 2 diabetic patients on renal replacement therapy (RRT). METHODS Patients who entere...

Background: While hepatocyte growth factor (HGF) is known to exert cell growth, migration and morphogenic effects in various organs, recent studies suggest that HGF may also play a role in synaptic maintenance and cerebrovascular integrity. Although increased levels of HGF have been reported in brain and cerebrospinal fluid (CSF) samples of patients with Alzheimer's disease (AD), it is unclear ...

Abstract Citrus exocortis viroid (CEVd), the causal agent of exocortis, is a pathogen that thought to infect all citrus varieties, although it asymptomatic in most. Symptoms develop on susceptible rootstocks, resulting stunting and yield reduction. To aid detection management CEVd, rapid near-field assay was developed using reverse transcription loop-mediated isothermal amplification (RT-LAMP) ...

Background and Aims: Citrus exocortis disease is naturally limited to citrus plants and causes a serious disease on sensitive rootstocks such as trifoliate orange. The aim of this study was to sample new variants of citrus exocortis viroid from Fars trees with yellowing and suberization symptoms and comparison with other isolates of this viroid. Materials and Methods: A number of symptomat...

AbstractBackground Existing cardiovascular risk scores for patients with established disease (CVD) estimate residual of recurrent major events (MACE). The aim the current study is to develop and externally validate a prediction model 10-year combined MACE interventions (MACE+) in CVD. Methods Data CVD from UCC-SMART cohort (N = 8421) were used development, pati...

22 23 2 SUMMARY 23 Citrus exocortis viroid (CEVd) populations are composed by closely related 24 haplotypes whose frequencies in the population result from the equilibrium 25 between mutation, selection and genetic drift. The genetic diversity of CEVd 26 populations infecting different citrus hosts was studied by comparing 27 populations recovered from infected trifoliate orange and sour orange...

Abstract Aims Little is known about the outcomes and processes of care patients with non ST-segment myocardial infarction (NSTEMI) who present “polyvascular” disease. Methods We analysed 287,279 NSTEMI using Myocardial Infarction National Audit Project (MINAP) registry. Clinical characteristics were according to history affected vascular bed; coronary artery disease (CAD), cerebrovascular (CeVD...

Viroids are small (246-401 nucleotides), single-stranded, circular RNA molecules that infect several crop plants and can cause diseases of economic importance. Citrus are the hosts in which the largest number of viroids have been identified. Citrus exocortis viroid (CEVd), the causal agent of citrus exocortis disease, induces considerable losses in citrus crops. Changes in the gene expression p...