Through the use of immunohistochemical techniques, human chorionic gonadotropin has been localized to syncytiotrophoblastic cells of immature placenta, hydatidiform mole, chorioadenoma destruens, and choriocarcinoma. No gonadotropin has been detected in cytotrophoblast. Evidence is discussed which suggests that syncytiotrophoblast is the cell of origin of human chorionic gonadotropin. The obser...

A new commercially available chemiluminescence immunoassay for the quantitative measurement of human chorionic gonadotropin and its beta-subunit in serum was compared with the enzyme immunoassay used in our routine laboratory. Human chorionic gonadotropin was determined in serum from pregnant women, as well as from women with abortus imminens, suspected ectopic pregnancies or with molar pregnan...

background: gonadotropin-releasing hormone agonists or antagonists are used in assisted reproductive technique cycles as premature luteinizing hormone secretion inhibition. studies have been reported different and contradictory results on the serum progesterone effect on intra-cytoplasmic sperm injection. objective: the purpose of this study was to evaluate the effect of serum progesterone leve...

Citation: Younis JS (2017) Commentary: Efficacy of Follicle-Stimulating Hormone (FSH) Alone, FSH + Luteinizing Hormone, Human Menopausal Gonadotropin or FSH + Human Chorionic Gonadotropin on Assisted Reproductive Technology Outcomes in the “Personalized” Medicine Era: A Meta-analysis. Front. Endocrinol. 8:264. doi: 10.3389/fendo.2017.00264 Commentary: efficacy of FollicleStimulating Hormone (FS...

A study was conducted to determine whether treatment with deslorelin, a gonadotropin-releasing hormone (GnRH) analog, produced anestrus in gilts and to test the ability of exogenous gonadotropin treatment with a combination of 400 IU equine chorionic gonadotropin and 200 IU human chorionic gonadotropin to induce estrus in GnRH analog-treated gilts. Twelve days after the third estrus, 11 gilts e...

Luteinizing hormone/human chorionic gonadotropin stimulates progesterone biosynthesis in the corpus luteum by activating cyclic adenosine monophosphate/protein kinase A cascade. Recent studies have shown that cyclic adenosine monophosphate-mediated activation of protein kinase A interacts with the mammalian target of rapamycin signaling pathways. Furthermore, the use of mammalian target of rapa...

Intraperitoneal injection of human chorionic gonadotropin in the rat induces a dose-dependent frequency of ovarian hyperemia. The occurrence of such hyperemia can be inhibited by pre-injection (3 hours) of antisera from rabbits immunized with gonadotropin extracts. It is demonstrated that the retained capacity of gonadotropin to induce hyperemia following antisera injections is greater when the...

OBJECTIVE To evaluate the relative importance of thyroid hormones and human chorionic gonadotropin in relation to the risk of gestational thyrotoxicosis in Saudi women living in Jeddah, Kingdom of Saudi Arabia. METHODS A prospective study was conducted on Saudi healthy pregnant women (N=406) at 12-15 weeks of gestation and compared with healthy non-pregnant controls (N=200). Maternal serum le...

background: abnormal oocyte morphology has been associated with the hormonal environment to which the gametes are exposed. objective: in this study, we evaluated the oocytes morphology, fertilization rate, embryos quality, and implantation rate resulted of retrieved oocytes in different times after human chorionic gonadotrophin (hcg) administration. materials and methods: a total of 985 metapha...