Hydrocephalus is an intractable disease characterized by the excessive accumulation of cerebrospinal fluid (CSF) in the cerebral ventricles. There are many cases in both human and animals; however, the cause and mechanism of it's development is not clearly understood. In this study, differences of cerebral ventricles in 5 inbred mice strains (MRL/MpJ, C57BL/6, C3H/He, DBA/2 and BALB/c) were inv...

Primary intracerebral fibrosarcomas are rare tumors of mesenchymal origin in the central nervous system (CNS). Fibrosarcoma presenting with spontaneous hemorrhage in the ventricles and without ventricle seeding has not been described in primary cerebral fibrosarcoma. We report the case of a 29-year-old male presenting with spontaneous hemorrhage of a fibrosarcoma that bled into the ventricles. ...

Large cerebral ventricles are a frequent finding in brains of dogs with brachycephalic skull conformation, in comparison with mesaticephalic dogs. It remains unclear whether oversized ventricles represent a normal variant or a pathological condition in brachycephalic dogs. There is a distinct relationship between white matter and grey matter in the cerebrum of all eutherian mammals. The aim of ...

drugs that could be used in conjunction with surgery to treat this debilitating neurological disease. receptor may be new therapeutic targets for developing 1 the fetal mice. These results suggest that LPA and its LPA receptor antagonist blocked the ability of LPA to induce hydrocephalus in 1 came with their demonstration that an LPA receptor, they were unable to induce hydrocephalus. The key f...