ighly active antiretroviral therapy (HAART) significantly educed the cerebral toxoplasmosis incidence in HIV-infected atients from high-income countries.1 However, there is carce epidemiological information about this neurological pportunistic disease in lowand middle-income countries, ncluding Brazil. In this letter, we would like to report some ssues about AIDS-related cerebral toxoplasmosis ...

Toxoplasmosis is a rare disease caused by intracellular protozoan parasite, Toxoplasma gondii. Though most patients with toxoplasmosis are asymptomatic, congenital toxoplasmosis in the fetus can cause ocular involvement such as chorioretinitis and central nervous system disease including intracerebral calcification, nystagmus, hydrocephalus and microcephaly. Also, these brain lesions can cause ...

A male intravenous drug abuser who was infected with hepatitis B and C, presented with a slowly progressive hemiplegia. Contrast enhanced computerized tomography of the head showed a solitary ring-enhanced mass with surrounding edema. Clinically brain tumor was suspected but a brain biopsy confirmed cerebral toxoplasmosis. An HIV test was not considered until the result of brain biopsy. He also...

•To consider differential diagnosis for multiple ring enhancing lesions in an immunocompromised patient.•To highlight the characteristic imaging features of toxoplasmosis: ‘‘concentric and eccentric target signs’’.•To radiologically demonstrate intracranial course oculomotor nerve its nucleus.•To lay stress on rare causes Weber’s syndrome: Cerebral toxoplasmosis our case. A 25-year-old male, HI...

We report a histologic and PCR-confirmed case of symptomatic congenital toxoplasmosis in premature infant with optic nerve atrophy severe ventriculomegaly requiring ventriculoperitoneal shunt the absence cerebral calcifications. A significant risk factor acquisition this infection was mother’s consumption raw deer meat during pregnancy.

PCR was used to evaluate the occurrence of Toxoplasma gondii parasitemia by detection of the B1 gene in blood samples in two groups of immunosuppressed patients (148 subjects) suspected of having cerebral or extracerebral infection, respectively. Group I consisted of 52 patients with AIDS with suspected cerebral toxoplasmosis. The diagnosis was clinically proven in 15 cases. Parasitemia was det...

Cerebral toxoplasmosis can be highly debilitating and occasionally fatal in persons with immune system deficiencies. In this study, we evaluated the Toxoplasma gondii-specific IgG subclass antibody response in 19 cerebrospinal fluid (CSF) samples from patients with cerebral toxoplasmosis who had a positive IgG anti-T. gondii ELISA standardized with a cyst antigen preparation. There were no sign...

BACKGROUND As the incidence of HIV infection has increased its neurological complications are being encountered in our clinical practice. Toxoplasmosis is a common cerebral opportunistic infection seen in HIV-infected patients, even though the incidence has declined with the use of antiretroviral therapy. Establishing a definitive diagnosis of cerebral toxoplasmosis is difficult in resource lim...