A 70-year-old female with a half-month history of schistosomiasis presented to a nonendemic region for treatment. Brain computed tomography (CT) and MRI revealed a lesion in the left occipital lobe; other clinical testing was not remarkable. The diagnosis was an intracranial occupying lesion in the left occipital lobe. After the removal of the brain lesion via cranial surgery, it was noticed th...

A. J. Idema, J. Wilbers, P. Krooshof, A. C. Koetsveld, P. Wesseling, W. van der Graaf, A. Gijtenbeek, W. Oyen, and A. Heerschap Neurosurgery, UMC St Radboud, Nijmegen, Gelderland, Netherlands, Neurology, UMC St Radboud, Netherlands, Analytical Chemistry, Institute for Molecules and Materials, Nijmegen, Netherlands, Pathology, UMC St Radboud, CWZ, Netherlands, Medical Oncology, UMC St Radboud, N...

BACKGROUND Cerebral involvement in schistosomiasis is not rare, but it is underdiagnosed because of the lack of clinical suspicion and the frequency of asymptomatic forms. Neurologic complications are generally supported by granuloma formation around ectopic eggs which have migrated to the brain. Moreover, vascular lesions and cerebral arteritis have been well documented in histopathological st...

Aspects of the pathogenesis of cerebral schistosomiasis have been elucidated. Arterial embolization alone, by either worms or eggs, does not appear to be likely as a major cause of the disease. When large numbers of eggs enter the brain, sensitization may play a role in the occurrence of neurological signs. These studies support but do not prove the theory that worms in the cerebral veins lay e...

since it was first diagnosed in 1914 in marrakesh, schistosomiasis has been a public health problem in morocco for decades. a national control program launched in 1982 has led to a considerable reduction in the incidence and morbidity associated with the disease. consequently, the program has shifted from disease control to an elimination process launched in 1994. this process aimed to eliminat...

Wild rodents have been used as animal models in experimental studies of cellular aging, cerebral malaria, schistosomiasis, and leishmaniasis. Since they are the reservoirs these diseases, recent shown that research involving wild is more efficient giving a mirror image disease progression outside laboratory setting. The study design was an analytic where observations were made between two group...

The first case of granulomatous choroiditis produced by Schistosoma mansoni with histological confirmation is reported. The patient had the hepatosplenic and cardiopulmonary forms of the disease and presented with cerebral schistosomiasis. The funduscopic aspects of the lesion and the possible pathways taken by the parasite to reach the choroid are discussed.

After returning from Africa, a 54-year-old man began to have episodes of headache and nausea, then a cerebral convulsion. Clinical and laboratory findings and response to chemotherapy indicated the diagnosis of cerebral schistosomiasis. Three lesions were seen on CT and MR studies: two appeared to be subacute intracerebral hematomas, one in the right parietal lobe and one in the frontal lobe; t...

The authors report a case of 36-year-old woman presented with epileptic seizures and headaches. Magnetic resonance imaging (MRI) revealed an enhancing lesion with surrounding edema and mild mass effect in the left frontal lobe. Stereotactic brain biopsy demonstrated intraparenchymal granulomas surrounding S. mansoni eggs. Praziquantel was started (60mg/kg of body weight, in a single dose), foll...

conclusions schistosomiasis is one of the major tropical and communicable diseases in the eastern mediterranean region (emr). however, today it is eliminated in iran by schistosomiasis control practices. results on the basis of our results, using a national program for schistosomiasis control based on active and passive case finding, snail control programs, education of people, conducting train...