introduction: sexual dimorphisms in biological structures such as brain and behaviour have been widely recognized in animals and humans. the purpose of this study was to examine whether there are sex differences in the size of the cerebellum with other body traits, such as the head, tail and brain. methods: twelve grasscutters comprising of 6 males and 6 females were used in this study. each br...

Antidepressant activity of crocin, saffron main component, has been established before. Based on previous study, it is suggested that elevation in the levels of BDNF (brain-derived neurotrophic factor), CREB (cAMP response element binding) and VGF neuropeptide could be considered as one probable molecular mechanisms involved in antidepressant activity of long term crocin administration in the r...

Drug abuse has been claimed to cause the loss of neurons and reduction of volume in both the adult and developing brain. This study examined cortex volumes in cerebrum and cerebellum of male rats that were dependent on morphine using unbiased stereological counting methods and systematic random sampling technique. Our goal was to test whether short time exposure to morphine can affect the corte...

　Introduction: Previous studies have suggested that the cerebellum is a primary site of motor learning. The cerebellar cortex has a particular glial architecture with large astroglial cells. In addition, more recent works have revealed that astrocytes play a more active role in neuronal activity. The aim of this study was to evaluate the number of astrocytes in the molecular layer of rat's cere...

Antidepressant activity of crocin, saffron main component, has been established before. Based on previous study, it is suggested that elevation in the levels of BDNF (brain-derived neurotrophic factor), CREB (cAMP response element binding) and VGF neuropeptide could be considered as one probable molecular mechanisms involved in antidepressant activity of long term crocin administration in the r...

objective(s): the present study aims at examining the motor coordination performance, serum and cerebellar estrogen, as well as erβ levels, of ovariectomized rats (as menopausal model) following regular exercise. materials and methods:ten female sprague dawley ratsaged 12 weeks old were randomly divided into two groups; all of which underwent ovariectomy. the first group was treated with regula...

most popular sources for electromagnetic waves. however, there are many concerns regarding their biological effects on the body, especially the central nervous system. therefore, the aim of this study was to evaluate the effects of cell phone radiation on histology of the cerebellar granular cells in the neonatal rat. materials and methods: we selected some wistar rats. then, we randomly divide...

•Chronic lead acetate toxicity was induced in male rats by oral administration.•Effect of Ocimum gratissimum on the cerebellum.•Oral administration led to oxidative stress cerebellum.•Ocimum extract attenuated and enhanced antioxidant enzymes.•Ocimum ameliorated acetate-induced cerebellum. ObjectivesLead (LA) is a known toxicant, its exposure environment has been increase recent times, leading ...

Reelin is an extracellular matrix neuroprotein which plays important roles during development and maturation of cerebellum. In the postnatal cerebellum, Reelin is synthesized by cerebellar granule cells and secreted to extracellular matrix. This secreted protein modulates adult synaptic function, neurotransmitter release and regulates plasticity. Exercise has beneficial effects on central nervo...