We present a miniature centrifuge force microscope (CFM) that repurposes a benchtop centrifuge for high-throughput single-molecule experiments with high-resolution particle tracking, a large force range, temperature control and simple push-button operation. Incorporating DNA nanoswitches to enable repeated interrogation by force of single molecular pairs, we demonstrate increased throughput, re...

1. A high speed centrifuge is described in which the speed is limited only by the strength of the material of which the rotor is made. It carries sixteen tubes, each of which conveniently accommodates 7 cc. of fluid. 2. The centrifuge operates in a very high vacuum and therefore requires only a small amount of driving energy. The arrangement has been found to eliminate the possibility of produc...

Bentonite-Sand Backfill is a part of Engineered Barrier System (EBS) widely used in a Near Surface Disposal Facility (NSDF) to delay migration of radionuclides from the disposed nuclear waste in a geo environment. Laboratory migration experiments have been conducted to understand the advection/diffusion mechanisms of various radionuclides through backfill and to evaluate their migration rates i...

INTRODUCTION Centrifuge-induced artificial gravity (AG) with exercise is a promising comprehensive countermeasure against the physiological de-conditioning that results from exposure to weightlessness. However, body movements onboard a rotating centrifuge are affected by both the gravity gradient and Coriolis accelerations. The effect of centrifugation on squat exercise biomechanics was investi...

Over the past 30 years, the PDCR-81 pore pressure transducer has become a standard instrument for measuring pore pressures in centrifuge experiments. Following the retirement of this transducer and its reduced reliability, it has become vital to find an alternative sensor for use by the geotechnical modelling community. In this paper, the response of the 2Mie pressure transducer is compared aga...

GENERALLY, the force of gravity has little or no effect upon the distribution of the various materials within cells, although they may differ considerably in their relative specific gravity. However, by means of the centrifuge forces can be obtained many times greater than gravity, which otherwise exist only on the very largest planets. Because of this fact, the centrifuge has proved to be a ve...

Micropiles (MP) are widely used for underpinning existing buildings that being vertically extended. They can be preloaded after installation, whereby partial loads transferred from existing...